Rabbit Polyclonal Integrin alpha5 antibody (STJ97284)

$99.00$319.00

Reactivity: Human, Mouse, Rat
Applications: WB, IHC, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Integrin alpha5 antibody (STJ97284)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IHC, ELISA

Recommended dilution: WB 1:500-1:2000; IHC-P 1:100-1:300; ELISA 1:10000;

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Integrin alpha5 Polyclonal Antibody.

Alternative names:

Check alternative names for the antibody

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ITGA5 antibody, FNRA antibody,|CD49 antigen-like family member E antibody|CD49e antibody|Fibronectin receptor subunit alpha antibody|Fibronectin receptor, alpha subunit antibody|FNRA antibody|Integrin alpha 5 (fibronectin receptor alpha) antibody|Integrin alpha-5 antibody|Integrin alpha-5 light chain antibody|Integrin alpha-F antibody|Integrin, alpha 5 (fibronectin receptor, alpha polypeptide) antibody|ITA5_HUMAN antibody|Itga5 antibody|Very late activation protein 5, alpha subunit antibody|VLA-5 antibody|VLA5 antibody|VLA5A antibody|Anti-Integrin alpha 5 antibody [EPR7854] (ab150361)
SCBT cat No: sc-19668|

 

Name

Integrin alpha5 Polyclonal Antibody

Catalogue No.

STJ97284

Reactivity

Human, Mouse, Rat

Specificity

Integrin alpha5 Polyclonal Antibody detects endogenous levels of Integrin alpha5 protein.

Immunogen

Synthesized peptide derived from Integrin alpha-5 at AA range 561-610

Host

Rabbit

Applications

WB, IHC, ELISA

Recommended dilution

WB 1:500-1:2000; IHC-P 1:100-1:300; ELISA 1:10000;

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Formulation

Integrin alpha5 Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

Integrin alpha5 Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Integrin alpha-5 antibody, CD49 antigen-like family member E antibody, Fibronectin receptor subunit alpha antibody, Integrin alpha-F antibody, VLA-5 antibody, CD antigen CD49e antibody

Database links

Human UniProt/Swiss-Prot:P08648;Rat UniProt/Swiss-Port: A0A0G2K1E2;Human Entrez Gene: 3678;Mouse Entrez Gene: 16402;Rat Entrez Gene: Rn.100796

Protein names

Integrin alpha-5 , CD49 antigen-like family member E , Fibronectin receptor subunit alpha , Integrin alpha-F , VLA-5 , CD antigen CD49e

Protein function

Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. / (Microbial infection) Integrin ITGA5:ITGB1 acts as a receptor for human metapneumovirus . Integrin ITGA2:ITGB1 acts as a receptor for human parvovirus B19 . In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi’s sarcoma lesions .

Protein sequence and domain

Belongs to the integrin alpha chain family. / Contains 7 FG-GAP repeats.

Protein post-translational modifications

Proteolytic cleavage by PCSK5 mediates activation of the precursor.

Protein cellular localization

Membrane; Single-pass type I membrane protein

Research area

All research areas>Cell Adhesion Proteins>Integrin alpha 5
(View all antibody categories related to Cell Adhesion Proteins)

Note

AntibodyPlus can customize Integrin alpha5 Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

Reviews


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Antibody customer reviews & validation data - 75

Validation data ID: 75

Submission date: 2017-01-20

View Details

Result figure:
Itga5.pdf

Figure description:

Integrin alpha5 is present in discreet puncta (likely represent focal adhesion complexes) at the tip of protrusions in zebrafish heart endocardial cells (overview and closeup attached)

Product name

Rabbit Polyclonal Integrin alpha5 antibody

Product catalog No.

STJ97284

Product type

Primary antibody

Supplier

St John's Laboratory Ltd

Application type

Immunofluorescence (IF)

Antibody specificity rating

Good

Antibody overall rating

Excellent

Your comments

Integrin alpha5 appears in discrete puncta at the tip of protrusions in migrating heart endocardial cells, similar to seen in cell cultures.
There is non-specific staining in the blood cells.

Detailed protocol

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