Rabbit polyclonal INTS6 antibody (A6634)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal INTS6 antibody (A6634)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal INTS6 antibody.

Alternative names:

Check alternative names for the antibody

Expand

HDB antibody, INT6 antibody, DBI-1 antibody, DDX26 antibody, DICE1 antibody, DDX26A antibody, Notchl2 antibody
DBI 1 antibody|DBI-1 antibody|DBI1 antibody|DDX26 antibody|DDX26A antibody|DEAD box protein antibody|DEAD/H (Asp Glu Ala Asp/His) box polypeptide 26 antibody|Deleted in cancer 1 antibody|DICE1 antibody|DKFZp434B105 antibody|HDB antibody|Int6 antibody|INT6_HUMAN antibody|Integrator complex subunit 6 antibody|INTS 6 antibody|ints6 antibody|Notchl2 antibody|OTTHUMP00000018439 antibody|OTTHUMP00000215034 antibody|OTTHUMP00000215036 antibody|Protein DDX26 antibody|Protein deleted in cancer 1 antibody|RNA helicase HDB antibody|Anti-DDX26 antibody (ab86369)

SCBT cat No: sc-292600|sc-376524|sc-101232|

Name

Rabbit polyclonal INTS6 antibody

Catalogue No.

A6634

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human INTS6

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 100kDa/Observed: Refer to Figures

Formulation

INTS6 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

INTS6 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

HDB antibody, INT6 antibody, DBI-1 antibody, DDX26 antibody, DICE1 antibody, DDX26A antibody, Notchl2 antibody

Database links

Human UniProt/Swiss-Prot:Q9UL03

Protein names

HDB, INT6, DBI-1, DDX26, DICE1, DDX26A, Notchl2

Protein function

Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3′-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. May have a tumor suppressor role; an ectopic expression suppressing tumor cell growth.

Protein tissue specificity

Widely expressed. Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.

Protein sequence and domain

Belongs to the Integrator subunit 6 family.; Contains 1 VWFA domain.

Protein cellular localization

Nucleus .

Background

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. The protein encoded by this gene is a DEAD box protein that is part of a complex that interacts with the C-terminus of RNA polymerase II and is involved in 3′ end processing of snRNAs. In addition, this gene is a candidate tumor suppressor and located in the critical region of loss of heterozygosity (LOH). Three transcript variants encoding two different isoforms have been found for this gene.

Note

AntibodyPlus can customize INTS6 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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