Rabbit polyclonal IRF6 antibody (A6246)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal IRF6 antibody (A6246)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

Expand

LPS antibody, PIT antibody, PPS antibody, VWS antibody, OFC6 antibody, PPS1 antibody, VWS1 antibody
Interferon regulatory factor 6 antibody|IRF 6 antibody|IRF-6 antibody|IRF6 antibody|IRF6_HUMAN antibody|LPS antibody|OFC 6 antibody|OFC6 antibody|OTTHUMP00000034677 antibody|OTTHUMP00000034678 antibody|PIT antibody|PPS antibody|PPS1 antibody|VWS antibody|VWS1 antibody|Anti-IRF6 antibody [2A12] (ab123880)

SCBT cat No: sc-30451|sc-30450|sc-377043|

Name

Rabbit polyclonal IRF6 antibody

Catalogue No.

A6246

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human IRF6

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 53kDa/Observed: Refer to Figures

Formulation

IRF6 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

IRF6 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

LPS antibody, PIT antibody, PPS antibody, VWS antibody, OFC6 antibody, PPS1 antibody, VWS1 antibody

Database links

Human UniProt/Swiss-Prot:O14896

Protein names

LPS, PIT, PPS, VWS, OFC6, PPS1, VWS1

Protein function

Probable DNA-binding transcriptional activator. Key determinant of the keratinocyte proliferation-differentiation switch involved in appropriate epidermal development (By similarity). Plays a role in regulating mammary epithelial cell proliferation (By similarity). May regulate WDR65 transcription (By similarity).

Protein tissue specificity

Expressed in normal mammary epithelial cells. Expression is reduced or absent in breast carcinomas.

Protein sequence and domain

Belongs to the IRF family.; Contains 1 IRF tryptophan pentad repeat DNA-binding domain.

Protein post-translational modifications

Phosphorylated. Phosphorylation status depends on the cell cycle and is a signal for ubiquitination and proteasome-mediated degradation.

Protein cellular localization

Nucleus . Cytoplasm . Note: Translocates to nucleus in response to an activating signal.

Background

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. The encoded protein may be a transcriptional activator. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. Mutations in this gene are also associated with non-syndromic orofacial cleft type 6. Alternate splicing results in multiple transcript variants.

Research area

All research areas>Transcription Regulators>IRF
(View all antibody categories related to Transcription Regulators)

Note

AntibodyPlus can customize IRF6 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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