Rabbit polyclonal ISL1 antibody (A6383)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal ISL1 antibody (A6383)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:100

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

Expand

Isl-1 antibody, ISLET1 antibody
Insulin gene enhancer protein ISL 1 antibody|ISL 1 antibody|ISL LIM homeobox 1 antibody|ISL1 antibody|ISL1 transcription factor LIM homeodomain antibody|ISL1 transcription factor, LIM/homeodomain (islet 1) antibody|ISL1 transcription factor, LIM/homeodomain antibody|ISL1_HUMAN antibody|Islet-1 antibody|Islet1 antibody|Anti-Islet 1 antibody – Neural Stem Cell Marker (ab20670)

SCBT cat No: sc-101072|sc-390793|sc-23590|sc-30200|

Name

Rabbit polyclonal ISL1 antibody

Catalogue No.

A6383

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human ISL1

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:100

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 39kDa/Observed: Refer to Figures

Formulation

ISL1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

ISL1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

Isl-1 antibody, ISLET1 antibody

Database links

Human UniProt/Swiss-Prot:P61371

Protein names

Isl-1, ISLET1

Protein function

Binds and regulates the promoters of the insulin, glucagon and somatostatin genes. Involved in the specificarion of motor neurons in cooperation with LHX3 and LDB1 (By similarity).

Protein tissue specificity

Expressed in subsets of neurons of the adrenal medulla and dorsal root ganglion, inner nuclear and ganglion cell layers in the retina, the pineal and some regions of the brain.

Protein sequence and domain

Contains 1 homeobox DNA-binding domain.; Contains 2 LIM zinc-binding domains.

Protein post-translational modifications

Phosphorylated.

Protein cellular localization

Nucleus.

Background

This gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young.

Research area

All research areas>Transcription Regulators>Islet
(View all antibody categories related to Transcription Regulators)

Note

AntibodyPlus can customize ISL1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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