Rabbit polyclonal ITGA2 antibody (A7629)

$69.00$259.00

Reactivity: Human
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal ITGA2 antibody (A7629)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:500 – 1:2000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

Expand

BR antibody, GPIa antibody, CD49B antibody, HPA-5 antibody, VLA-2 antibody, VLAA2 antibody
BR antibody|CD 49b antibody|CD49 antigen like family member B antibody|CD49 antigen-like family member B antibody|CD49b antibody|CD49b antigen antibody|Collagen receptor antibody|DX5 antibody|Glycoprotein Ia deficiency included antibody|GP Ia antibody|GP Ia deficiency, included antibody|GPIa antibody|HPA 5 included antibody|HPA5 included antibody|Human platelet alloantigen system 5 antibody|Integrin alpha 2 antibody|Integrin alpha-2 antibody|Integrin, alpha 2 (CD49B alpha 2 subunit of VLA 2 receptor) antibody|ITA2_HUMAN antibody|ITGA2 antibody|Platelet alloantigen Br(a), included antibody|Platelet antigen Br antibody|Platelet glycoprotein GPIa antibody|Platelet glycoprotein Ia antibody|Platelet glycoprotein Ia/IIa antibody|Platelet membrane glycoprotein Ia antibody|Platelet receptor for collagen, deficiency of, included antibody|Very late activation protein 2 receptor alpha 2 subunit antibody|VLA 2 alpha chain antibody|VLA 2 antibody|VLA 2 subunit alpha antibody|VLA-2 subunit alpha antibody|VLA2 antibody|VLA2 receptor alpha 2 subunit antibody|VLAA2 antibody|Anti-Integrin alpha 2 antibody [EPR5788] (ab133557)

SCBT cat No: sc-136257|sc-74466|sc-9089|sc-53352|sc-53353|sc-6586|sc-53502|sc-13546|sc-53506|

Name

Rabbit polyclonal ITGA2 antibody

Catalogue No.

A7629

Reactivity

Human

Immunogen

Recombinant protein of human ITGA2

Host

Rabbit

Applications

WB

Recommended dilution

WB 1:500 – 1:2000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 129kDa/Observed: Refer to figures

Formulation

ITGA2 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

ITGA2 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

BR antibody, GPIa antibody, CD49B antibody, HPA-5 antibody, VLA-2 antibody, VLAA2 antibody

Database links

Human UniProt/Swiss-Prot:P17301

Protein names

BR, GPIa, CD49B, HPA-5, VLA-2, VLAA2

Protein function

Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix.; (Microbial infection) Integrin ITGA2:ITGB1 acts as a receptor for human rotavirus A . Integrin ITGA2:ITGB1 acts as a receptor for human echoviruses 1 and 8 .

Protein sequence and domain

The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage.Belongs to the integrin alpha chain family.; Contains 7 FG-GAP repeats.; Contains 1 VWFA domain.

Protein cellular localization

Membrane; Single-pass type I membrane protein.

Background

This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants.

Research area

All research areas>Cell Adhesion Proteins>Integrin
(View all antibody categories related to Cell Adhesion Proteins)

Note

AntibodyPlus can customize ITGA2 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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