Rabbit polyclonal ITGAM antibody (A1581)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal ITGAM antibody (A1581)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal ITGAM antibody.

Alternative names:

Check alternative names for the antibody

Expand

CR3A antibody, MO1A antibody, CD11B antibody, MAC-1 antibody, MAC1A antibody, SLEB6 antibody
Antigen CD11A (p180), lymphocyte function associated antigen 1, alpha polypeptide antibody|CD11 antigen-like family member A antibody|CD11a antibody|CD18 antibody|CR3 antibody|Integrin alpha-L antibody|Integrin beta 2 antibody|Integrin gene promoter antibody|ITAL_HUMAN antibody|Itgal antibody|ITGAM antibody|ITGB2 antibody|LAD antibody|Leukocyte adhesion glycoprotein LFA-1 alpha chain antibody|Leukocyte function-associated molecule 1 alpha chain antibody|LFA 1 alpha antibody|LFA 1 antibody|LFA-1A antibody|LFA1 antibody|LFA1A antibody|Lymphocyte function associated antigen 1 antibody|MAC1 antibody|MFI7 antibody|MO1A antibody|Anti-CD11+CD18 antibody [24] (ab13219)

SCBT cat No: sc-71404|sc-71399|sc-71405|sc-71398|sc-59747|sc-6623|sc-393790|sc-65874|

Name

Rabbit polyclonal ITGAM antibody

Catalogue No.

A1581

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human ITGAM

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 127kDa/Observed: Refer to Figures

Formulation

ITGAM antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

ITGAM antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

CR3A antibody, MO1A antibody, CD11B antibody, MAC-1 antibody, MAC1A antibody, SLEB6 antibody

Database links

Human UniProt/Swiss-Prot:P11215

Protein names

CR3A, MO1A, CD11B, MAC-1, MAC1A, SLEB6

Protein function

Integrin alpha-M/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha-M/beta-2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain.

Protein tissue specificity

Predominantly expressed in monocytes and granulocytes.

Protein sequence and domain

The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage.Belongs to the integrin alpha chain family.; Contains 7 FG-GAP repeats.; Contains 1 VWFA domain.

Protein cellular localization

Membrane; Single-pass type I membrane protein.

Background

ITGAM, also named as CD11B and CR3A, belongs to the integrin alpha chain family. It is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. ITGAM is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. It is also a receptor for fibrinogen, factor X and ICAM1. ITGAM recognizes P1 and P2 peptides of fibrinogen gamma chain.

Research area

All research areas>Cell Adhesion Proteins>Integrin
(View all antibody categories related to Cell Adhesion Proteins)

Note

AntibodyPlus can customize ITGAM antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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