Rabbit Polyclonal JTB antibody (A10427)

$99.00$259.00

Reactivity: Human,Rat
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit Polyclonal JTB antibody (A10427)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:500 – 1:2000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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PAR antibody; hJT antibody; HJTB antibody; HSPC222 antibody;
hJT antibody|HJTB antibody|HSPC222 antibody|JTB antibody|JTB_HUMAN antibody|Jumping translocation breakpoint antibody|Jumping translocation breakpoint protein antibody|OTTHUMP00000034759 antibody|PAR antibody|PAR protein antibody|Prostate androgen regulated protein antibody|Prostate androgen-regulated protein antibody|Protein JTB antibody|Anti-JTB antibody (ab137008)

SCBT cat No:

Name

Rabbit Polyclonal JTB antibody

Catalogue No.

A10427

Reactivity

Human, Rat

Immunogen

Recombinant protein of human JTB

Host

Rabbit

Applications

WB

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

16kDa

Formulation

JTB antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

Affinity purification

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

PAR antibody; hJT antibody; HJTB antibody; HSPC222 antibody;

Protein names

PAR; hJT; HJTB; HSPC222;

Protein function

Required for normal cytokinesis during mitosis. Plays a role in the regulation of cell proliferation. May be a component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Increases AURKB activity. Inhibits apoptosis induced by TGFB1 (By similarity). Overexpression induces swelling of mitochondria and reduces mitochondrial membrane potential (By similarity).

Protein tissue specificity

Ubiquitous. Expressed in all normal human tissues studied but overexpressed or underexpressed in many of their malignant counterparts.

Protein sequence and domain

Belongs to the JTB family.

Protein cellular localization

Membrane ; Single-pass type I membrane protein . Mitochondrion . Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Note=Detected at the centrosome and along spindle fibers during prophase and metaphase. Detected at the midbody during telophase.

Note

AntibodyPlus can customize JTB antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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