Rabbit polyclonal JUP antibody (A0963)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal JUP antibody (A0963)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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JUP antibody,ARVD12 antibody,CTNNG antibody,DP3 antibody,DPIII antibody,PDGB antibody,PKGB antibody
ARVD 12 antibody|ARVD12 antibody|Catenin (cadherin associated protein), gamma 80kDa antibody|catenin (cadherin-associated protein) gamma (80kD) antibody|Catenin gamma antibody|CTNNG antibody|Desmoplakin 3 antibody|Desmoplakin III antibody|Desmoplakin-3 antibody|Desmoplakin3 antibody|DesmoplakinIII antibody|DP 3 antibody|DP III antibody|DP3 antibody|DPIII antibody|gamma catenin antibody|Junction plakoglobin antibody|JUP antibody|OTTHUMP00000164732 antibody|OTTHUMP00000164735 antibody|OTTHUMP00000164738 antibody|PDGB antibody|PKGB antibody|PLAK_HUMAN antibody|PLAKOGLOBIN antibody|Anti-gamma Catenin antibody [EPR17310] (ab184919)

SCBT cat No: sc-59986|sc-33634|sc-514115|sc-514130|sc-1497|sc-398183|sc-514116|sc-30998|sc-8415|sc-7900|sc-30997|sc-30996|

Name

Rabbit polyclonal JUP antibody

Catalogue No.

A0963

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human JUP

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 82kDa/Observed: Refer to Figures

Formulation

JUP antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

JUP antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

JUP antibody,ARVD12 antibody,CTNNG antibody,DP3 antibody,DPIII antibody,PDGB antibody,PKGB antibody

Database links

Human UniProt/Swiss-Prot:P14923

Protein names

JUP,ARVD12,CTNNG,DP3,DPIII,PDGB,PKGB

Protein function

Common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE-cadherin function in endothelial cells. Can replace beta-catenin in E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton (By similarity).

Protein sequence and domain

The entire ARM repeats region mediates binding to CDH1/E-cadherin. The N-terminus and first three ARM repeats are sufficient for binding to DSG1. The N-terminus and first ARM repeat are sufficient for association with CTNNA1. DSC1 association requires both ends of the ARM repeat region.Belongs to the beta-catenin family.; Contains 12 ARM repeats.

Protein post-translational modifications

May be phosphorylated by FER.

Protein cellular localization

Cell junction, adherens junction . Cell junction, desmosome . Cytoplasm, cytoskeleton . Membrane ; Peripheral membrane protein . Note: Cytoplasmic in a soluble and membrane-associated form.

Background

This gene encodes a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat. Mutation in this gene has been associated with Naxos disease. Alternative splicing occurs in this gene; however, not all transcripts have been fully described. [provided by RefSeq, Jul 2008]

Research area

All research areas>Cell Adhesion Proteins>Catenin
(View all antibody categories related to Cell Adhesion Proteins)

Note

AntibodyPlus can customize JUP antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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