Rabbit polyclonal KCND3 antibody (A6927)


Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal KCND3 antibody (A6927)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody


KV4.3 antibody, SCA19 antibody, SCA22 antibody, KCND3L antibody, KCND3S antibody, KSHIVB antibody
KCND 3 antibody|Potassium voltage gated channel subfamily D member 3 antibody|Voltage gated K+ channel antibody|Voltage gated potassium channel Kv4.3 antibody|Voltage gated potassium channel subunit Kv4.3 antibody|Voltage-gated potassium channel subunit Kv4.3 antibody|Anti-Kv4.3 antibody [S75-41] (ab99045)

SCBT cat No: sc-11686|


Rabbit polyclonal KCND3 antibody

Catalogue No.



Human, Mouse, Rat


Recombinant protein of human KCND3





Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200







Molecular weight

Predicted: 73kDa/Observed: Refer to figures


KCND3 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.


KCND3 antibody was purified using affinity purification.


Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

KV4.3 antibody, SCA19 antibody, SCA22 antibody, KCND3L antibody, KCND3S antibody, KSHIVB antibody

Database links

Human UniProt/Swiss-Prot:Q9UK17

Protein names


Protein function

Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels. May contribute to I(To) current in heart and I(Sa) current in neurons. Channel properties are modulated by interactions with other alpha subunits and with regulatory subunits.

Protein tissue specificity

Highly expressed in heart and brain, in particular in cortex, cerebellum, amygdala and caudate nucleus. Detected at lower levels in liver, skeletal muscle, kidney and pancreas. Isoform 1 predominates in most tissues. Isoform 1 and isoform 2 are detected at similar levels in brain, skeletal muscle and pancreas.

Protein sequence and domain

The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position.Belongs to the potassium channel family. D (Shal) (TC 1.A.1.2) subfamily. Kv4.3/KCND3 sub-subfamily.

Protein post-translational modifications

Regulated through phosphorylation at Ser-569 by CaMK2D.

Protein cellular localization

Cell membrane ; Multi-pass membrane protein . Cell membrane, sarcolemma ; Multi-pass membrane protein . Cell projection, dendrite . Note: Interaction with palmitoylated KCNIP2 and KCNIP3 enhances cell surface expression.


Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes – shaker, shaw, shab, and shal – have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This member includes two isoforms with different sizes, which are encoded by alternatively spliced transcript variants of this gene.

Research area

All research areas>Channel Proteins>KV
(View all antibody categories related to Channel Proteins)


AntibodyPlus can customize KCND3 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody


ABclonal Inc.


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