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Rabbit polyclonal KCNIP2 antibody (A7100)
Supplier: ABclonal Inc.
Recommended applications: WB,IHC
WB 1:500 – 1:2000 IHC 1:50 – 1:200
Recommended protocols: check protocols
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Check alternative names for the antibodyExpand
A type potassium channel modulatory protein 2 antibody|A-type potassium channel modulatory protein 2 antibody|Cardiac voltage gated potassium channel modulatory subunit antibody|Cardiac voltage-gated potassium channel modulatory subunit antibody|DKFZp566L1246 antibody|KChIP 2 antibody|KChIP2 antibody|KCIP2_HUMAN antibody|KCNIP 2 antibody|Kcnip2 antibody|Kv channel interacting protein 2 antibody|Kv channel-interacting protein 2 antibody|MGC17241 antibody|Potassium channel interacting protein 2 antibody|Potassium channel-interacting protein 2 antibody|Anti-KChIP2 antibody [S60-73] (ab99041)
SCBT cat No: sc-134371|sc-26469|sc-26467|sc-25685|
Rabbit polyclonal KCNIP2 antibody
|Catalogue No.|| |
Recombinant protein of human KCNIP2
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
Predicted: 31kDa/Observed: Refer to figures
KCNIP2 antibody was tube-contained.
KCNIP2 antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Alternative antibody names|| |
|Database links|| |
|Protein names|| |
|Protein function|| |
Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Modulates channel density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner. In vitro, modulates KCND2/Kv4.2 and KCND3/Kv4.3 currents. Involved in KCND2 and KCND3 trafficking to the cell surface. May be required for the expression of I(To) currents in the heart (By similarity).
|Protein tissue specificity|| |
Expressed in brain. Colocalizes with KCND2 in excitatory neurons including cortical and hippocampal CA1 pyramidal cells. Isoform 3 is expressed in heart and in umbilical vein endothelial cells. Not expressed in fetal heart.
|Protein sequence and domain|| |
Belongs to the recoverin family.; Contains 4 EF-hand domains.
|Protein post-translational modifications|| |
Palmitoylated. Palmitoylation enhances association with the plasma membrane.
|Protein cellular localization|| |
Isoform 1: Cell membrane ; Lipid-anchor . Note: Detected on lipid rafts (By similarity).; Isoform 2: Cell membrane ; Lipid-anchor .; Isoform 6: Cell membrane ; Lipid-anchor .
This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belongs to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified from this gene.
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|Product type|| |
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