Rabbit polyclonal KDM5B antibody (A7772)

$69.00$259.00

Reactivity: Human
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal KDM5B antibody (A7772)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:500 – 1:2000

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal KDM5B antibody.

Alternative names:

Check alternative names for the antibody

Expand

CT31 antibody, PLU1 antibody, PUT1 antibody, PLU-1 antibody, JARID1B antibody, PPP1R98 antibody, RBBP2H1A antibody
Cancer/testis antigen 31 antibody|CT31 antibody|Histone demethylase JARID1B antibody|JARID1B antibody|Jumonji AT rich interactive domain 1B antibody|Jumonji/ARID domain-containing protein 1B antibody|Kdm5b antibody|KDM5B_HUMAN antibody|Lysine (K) specific demethylase 5B antibody|Lysine demethylase 5B antibody|Lysine specific demethylase 5B antibody|Lysine-specific demethylase 5B antibody|PLU-1 antibody|PLU1 antibody|PPP1R98 antibody|Protein phosphatase 1 regulatory subunit 98 antibody|PUT1 antibody|putative DNA/chromatin binding motif antibody|RBBP2H1A antibody|RBP2 like antibody|RBP2-H1 antibody|Retinoblastoma-binding protein 2 homolog 1 antibody|Retinoblastoma-binding protein 2 homolog 1A antibody|Anti-KDM5B / PLU1 / Jarid1B antibody (ab56759)

SCBT cat No: sc-67035|sc-81358|sc-31612|sc-31613|

Name

Rabbit polyclonal KDM5B antibody

Catalogue No.

A7772

Reactivity

Human

Immunogen

Recombinant protein of human KDM5B

Host

Rabbit

Applications

WB

Recommended dilution

WB 1:500 – 1:2000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 176kDa/Observed: Refer to figures

Formulation

KDM5B antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

KDM5B antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

CT31 antibody, PLU1 antibody, PUT1 antibody, PLU-1 antibody, JARID1B antibody, PPP1R98 antibody, RBBP2H1A antibody

Database links

Human UniProt/Swiss-Prot:Q9UGL1

Protein names

CT31, PLU1, PUT1, PLU-1, JARID1B, PPP1R98, RBBP2H1A

Protein function

Histone demethylase that demethylates ‘Lys-4’ of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 ‘Lys-9’ or H3 ‘Lys-27’. Demethylates trimethylated, dimethylated and monomethylated H3 ‘Lys-4’. Acts as a transcriptional corepressor for FOXG1B and PAX9. Favors the proliferation of breast cancer cells by repressing tumor suppressor genes such as BRCA1 and HOXA5. In contrast, may act as a tumor suppressor for melanoma. Represses the CLOCK-ARNTL/BMAL1 heterodimer-mediated transcriptional activation of the core clock component PER2 (By similarity).

Protein tissue specificity

Ubiquitously expressed, with highest levels in testis. Down-regulated in melanoma and glioblastoma. Up-regulated in breast cancer (at protein level).

Protein sequence and domain

Both the JmjC domain and the JmjN domain are required for enzymatic activity.; The 2 first PHD-type zinc finger domains are required for transcription repression activity.Belongs to the JARID1 histone demethylase family.; Contains 1 ARID domain.; Contains 1 JmjC domain.; Contains 1 JmjN domain.; Contains 3 PHD-type zinc fingers.

Protein cellular localization

Nucleus .

Note

AntibodyPlus can customize KDM5B antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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