Rabbit polyclonal KHDRBS2 antibody (A6102)

$69.00$259.00

Reactivity: Human
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal KHDRBS2 antibody (A6102)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:1000 IHC 1:100 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal KHDRBS2 antibody.

Alternative names:

Check alternative names for the antibody

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SLM1 antibody, SLM-1 antibody, bA535F17.1 antibody
KH domain containing, RNA binding, signal transduction associated protein 2 antibody|6330586C16Rik antibody|bA535F17.1 antibody|FLJ38664 antibody|hSLM 1 antibody|hSLM-1 antibody|KH domain containing, RNA binding, signal transduction associated 2 antibody|KH domain-containing antibody|KHDR2_HUMAN antibody|khdrbs2 antibody|MGC26664 antibody|RNA-binding antibody|Sam68 like mammalian protein 1 antibody|Sam68-like mammalian protein 1 antibody|signal transduction-associated protein 2 antibody|SLM 1 antibody|SLM-1 antibody|SLM1 antibody|Anti-KHDRBS2 antibody [7G8C10] – C-terminal (ab201982)

SCBT cat No:

Name

Rabbit polyclonal KHDRBS2 antibody

Catalogue No.

A6102

Reactivity

Human

Immunogen

A synthetic peptide of human KHDRBS2

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:1000
IHC 1:100 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 38kDa/Observed: Refer to Figures

Formulation

KHDRBS2 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

KHDRBS2 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

SLM1 antibody, SLM-1 antibody, bA535F17.1 antibody

Database links

Human UniProt/Swiss-Prot:Q5VWX1

Protein names

SLM1, SLM-1, bA535F17.1

Protein function

RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Binds both poly(A) and poly(U) homopolymers. Phosphorylation by PTK6 inhibits its RNA-binding ability (By similarity). Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. Can regulate alternative splicing of NRXN1 in the laminin G-like domain 6 containing the evolutionary conserved neurexin alternative spliced segment 4 (AS4) involved in neurexin selective targeting to postsynaptic partners. Regulates cell-type specific alternative splicing of NRXN1 at AS4 and acts synergystically with SAM68 in exon skipping. In contrast acts antagonistically with SAM68 in NRXN3 exon skipping at AS4. Its phosphorylation by FYN inhibits its ability to regulate splice site selection. May function as an adapter protein for Src kinases during mitosis.

Protein tissue specificity

Highly expressed in brain, lung, kidney and small intestine. Weakly expressed in placenta, liver, spleen, thymus, ovary and colon.

Protein sequence and domain

Belongs to the KHDRBS family.; Contains 1 KH domain.

Protein post-translational modifications

Methylated.; Tyrosine phosphorylated by FYN, PTK6 and SRC. Tyrosine phosphorylated by SRC during mitosis (By similarity).

Protein cellular localization

Nucleus .

Note

AntibodyPlus can customize KHDRBS2 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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