Rabbit polyclonal KHDRBS3 antibody (A6637)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

Clear
-$50 as credit for submitting review for primary antibody
Shipping notice:
Product will be delivered in 6 to 8 Business Days

Rabbit polyclonal KHDRBS3 antibody (A6637)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal KHDRBS3 antibody.

Alternative names:

Check alternative names for the antibody

Expand

Etle antibody, SALP antibody, SLM2 antibody, SLM-2 antibody, TSTAR antibody, T-STAR antibody, etoile antibody
Etle antibody|etoile antibody|KH domain containing RNA binding signal transduction associated 3 antibody|KH domain containing RNA binding signal transduction associated protein 3 antibody|KH domain-containing antibody|KHDR3_HUMAN antibody|Khdrbs3 antibody|RNA binding protein T Star antibody|RNA-binding antibody|RNA-binding protein T-Star antibody|SALP antibody|Sam68 like mammalian protein 2 antibody|Sam68 like phosphotyrosine protein antibody|Sam68 like phosphotyrosine protein T STAR antibody|Sam68-like mammalian protein 2 antibody|Sam68-like phosphotyrosine protein antibody|signal transduction-associated protein 3 antibody|SLM 2 antibody|SLM-2 antibody|SLM2 antibody|T STAR antibody|TSTAR antibody|Anti-KHDRBS3 antibody (ab68515)

SCBT cat No:

Name

Rabbit polyclonal KHDRBS3 antibody

Catalogue No.

A6637

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human KHDRBS3

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 39kDa/Observed: Refer to figures

Formulation

KHDRBS3 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

KHDRBS3 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

Etle antibody, SALP antibody, SLM2 antibody, SLM-2 antibody, TSTAR antibody, T-STAR antibody, etoile antibody

Database links

Human UniProt/Swiss-Prot:O75525

Protein names

Etle, SALP, SLM2, SLM-2, TSTAR, T-STAR, etoile

Protein function

RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Binds preferentially to the 5′-[AU]UAAA-3′ motif in vitro. Binds optimally to RNA containing 5′-[AU]UAA-3′ as a bipartite motif spaced by more than 15 nucleotides. Binds poly(A). RNA-binding abilities are down-regulated by tyrosine kinase PTK6 . Involved in splice site selection of vascular endothelial growth factor . In vitro regulates CD44 alternative splicing by direct binding to purine-rich exonic enhancer (By similarity). Can regulate alternative splicing of neurexins NRXN1-3 in the laminin G-like domain 6 containing the evolutionary conserved neurexin alternative spliced segment 4 (AS4) involved in neurexin selective targeting to postsynaptic partners such as neuroligins and LRRTM family members . Targeted, cell-type specific splicing regulation of NRXN1 at AS4 is involved in neuronal glutamatergic synapse function and plasticity (By similarity). May regulate expression of KHDRBS2/SLIM-1 in defined brain neuron populations by modifying its alternative splicing (By similarity). Can bind FABP9 mRNA (By similarity). May play a role as a negative regulator of cell growth. Inhibits cell proliferation.; (Microbial infection) Involved in post-transcriptional regulation of HIV-1 gene expression.

Protein tissue specificity

Ubiquitous with higher expression in testis, skeletal muscle and brain. Expressed in the kidney only in podocytes, the glomerular epithelial cells of the kidney. Strongly expressed after meiosis.

Protein sequence and domain

The proline-rich site binds the SH3 domain of the p85 subunit of PI3-kinase.Belongs to the KHDRBS family.; Contains 1 KH domain.

Protein post-translational modifications

Phosphorylated on tyrosine residues. Isoform 1 C-terminal region is tyrosine-rich, but isoform 2 lacking this C-terminal region is also tyrosine-phosphorylated.

Protein cellular localization

Nucleus . Note: Localized in a compartment adjacent to the nucleolus, but distinct from the peri-nucleolar one.

Note

AntibodyPlus can customize KHDRBS3 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

Reviews


There are no reviews yet.

Only logged in customers who have purchased this product may leave a review

There are no reviews for this product yet.
By submitting a review, get following benefits:

1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!

view database submit reviews

There is no extra validation for this product yet.
Check other extra validated antibodies below:



Welcome to AntibodyPlus!