Rabbit polyclonal KIF4A antibody (A10193)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal KIF4A antibody (A10193)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:1000 – 1:3000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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Chromokinesin antibody|Chromokinesin-A antibody|Chromosome associated kinesin KIF4A antibody|Chromosome-associated kinesin KIF4A antibody|FLJ12530 antibody|FLJ12655 antibody|FLJ14204 antibody|FLJ20631 antibody|HSA271784 antibody|KIF4 antibody|KIF4 G1 antibody|KIF4A antibody|KIF4A_HUMAN antibody|KIF4G1 antibody|Kinesin family member 4A antibody|Anti-KIF4A antibody (ab3815)

SCBT cat No: sc-365145|sc-365144|

Name

Rabbit polyclonal KIF4A antibody

Catalogue No.

A10193

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human KIF4A

Host

Rabbit

Applications

WB

Recommended dilution

WB 1:1000 – 1:3000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 140kDa/Observed: Refer to figures

Formulation

KIF4A antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

KIF4A antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Database links

Human UniProt/Swiss-Prot:O95239

Protein function

Motor protein that translocates PRC1 to the plus ends of interdigitating spindle microtubules during the metaphase to anaphase transition, an essential step for the formation of an organized central spindle midzone and midbody and for successful cytokinesis. May play a role in mitotic chromosomal positioning and bipolar spindle stabilization.

Protein tissue specificity

Highly expressed in hematopoietic tissues, fetal liver, spleen, thymus and adult thymus and bone marrow. Lower levels are found in heart, testis, kidney, colon and lung.

Protein sequence and domain

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. Chromokinesin subfamily.; Contains 1 kinesin motor domain.

Protein cellular localization

Nucleus matrix. Cytoplasm, cytoskeleton, spindle. Midbody. Chromosome. Note: Not present in the nucleolus. In early mitosis, associated with the mitotic spindle, in anaphase, localized to the spindle midzone and, in telophase and cytokinesis, to the midbody. In late cytokinesis, found in the center of the midbody. Associated with chromosomes at all stages of mitosis.

Background

This gene encodes a member of the kinesin 4 subfamily of kinesin related proteins. The encoded protein is an ATP dependent microtubule-based motor protein that is involved in the intracellular transport of membranous organelles. This protein also associates with condensed chromosome arms and may be involved in maintaining chromosome integrity during mitosis. This protein may also be involved in the organization of the central spindle prior to cytokinesis. A pseudogene of this gene is found on chromosome X.[provided by RefSeq, Mar 2010]

Research area

All research areas>Structural Proteins>KIF
(View all antibody categories related to Structural Proteins)

Note

AntibodyPlus can customize KIF4A antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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