Rabbit polyclonal KIR2DL3 antibody (A1698)

$69.00$259.00

Reactivity: Human
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal KIR2DL3 antibody (A1698)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal KIR2DL3 antibody.

Alternative names:

Check alternative names for the antibody

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p58 antibody, NKAT antibody, GL183 antibody, NKAT2 antibody, CD158b antibody, NKAT2A antibody, NKAT2B antibody, CD158B2 antibody, KIR-K7b antibody, KIR-K7c antibody, KIRCL23 antibody, KIR-023GB antibody
CD158 antigen like family member B2 antibody|CD158 antigen-like family member B2 antibody|CD158b antibody|CD158b2 antibody|GL183 antibody|KI2L3_HUMAN antibody|Killer cell immunoglobulin like receptor two domains long cytoplasmic tail 3 antibody|Killer cell immunoglobulin-like receptor 2DL3 antibody|Killer inhibitory receptor cl 2-3 antibody|Killer inhibitory receptor CL2 3 antibody|KIR 023GB antibody|KIR-023GB antibody|KIR-K7b antibody|KIR-K7c antibody|KIR023GB antibody|KIR2DL3 antibody|KIR2DS5 antibody|KIRCL23 antibody|MHC class I NK cell receptor antibody|Natural killer associated transcript 2 antibody|Natural killer cell inhibitory receptor KIR2DL3 antibody|Natural killer-associated transcript 2 antibody|NKAT antibody|NKAT-2 antibody|NKAT2 antibody|NKAT2a antibody|NKAT2b antibody|p58 antibody|p58 natural killer cell receptor clone CL 6 antibody|p58 natural killer cell receptor clone CL-6 antibody|p58 NK Receptor antibody|p58 NK receptor CL 6 antibody|p58 NK receptor CL-6 antibody|p58.2 MHC class I specific NK receptor antibody|p58.2 MHC class-I-specific NK receptor antibody|Anti-KIR2DL3 antibody (ab180803)

SCBT cat No: sc-71467|sc-59274|sc-71466|sc-398606|

Name

Rabbit polyclonal KIR2DL3 antibody

Catalogue No.

A1698

Reactivity

Human

Immunogen

Recombinant protein of human KIR2DL3

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 38kDa/Observed: Refer to Figures

Formulation

KIR2DL3 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

KIR2DL3 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

p58 antibody, NKAT antibody, GL183 antibody, NKAT2 antibody, CD158b antibody, NKAT2A antibody, NKAT2B antibody, CD158B2 antibody, KIR-K7b antibody, KIR-K7c antibody, KIRCL23 antibody, KIR-023GB antibody

Database links

Human UniProt/Swiss-Prot:P43628

Protein names

p58, NKAT, GL183, NKAT2, CD158b, NKAT2A, NKAT2B, CD158B2, KIR-K7b, KIR-K7c, KIRCL23, KIR-023GB

Protein function

Receptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3 and HLA-Cw7). Inhibits the activity of NK cells thus preventing cell lysis.

Protein sequence and domain

Belongs to the immunoglobulin superfamily.; Contains 2 Ig-like C2-type (immunoglobulin-like) domains.

Protein cellular localization

Cell membrane; Single-pass type I membrane protein.

Background

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several “framework” genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response. [provided by RefSeq, Jul 2008]

Research area

All research areas>Lymphocyte Signaling>KIRD
(View all antibody categories related to Lymphocyte Signaling)

Note

AntibodyPlus can customize KIR2DL3 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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