Rabbit polyclonal KLC1 antibody (A5552)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal KLC1 antibody (A5552)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal KLC1 antibody.

Alternative names:

Check alternative names for the antibody

Expand

KLC antibody, KNS2 antibody, KNS2A antibody, RP11-73M18.7 antibody, RP11-73M18.8 antibody
Kinesin 2 60/70kDa antibody|Kinesin light chain 1 antibody|Kinesin2 antibody|KLC 1 antibody|KLC antibody|Klc1 antibody|KLC1_HUMAN antibody|KNS 2 antibody|KNS 2A antibody|KNS2 antibody|KNS2A antibody|Medulloblastoma antigen MU MB 2.50 antibody|MGC15245 antibody|Anti-KLC1 antibody [EPR12441(B)] (ab174273)

SCBT cat No: sc-25735|sc-13361|sc-58776|sc-13362|

Name

Rabbit polyclonal KLC1 antibody

Catalogue No.

A5552

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human KLC1

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 65kDa/Observed: Refer to Figures

Formulation

KLC1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

KLC1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

KLC antibody, KNS2 antibody, KNS2A antibody, RP11-73M18.7 antibody, RP11-73M18.8 antibody

Database links

Human UniProt/Swiss-Prot:Q07866

Protein names

KLC, KNS2, KNS2A, RP11-73M18.7, RP11-73M18.8

Protein function

Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. The light chain may function in coupling of cargo to the heavy chain or in the modulation of its ATPase activity.

Protein tissue specificity

Found in a variety of tissues. Mostly abundant in brain and spine.

Protein sequence and domain

Belongs to the kinesin light chain family.; Contains 6 TPR repeats.

Protein post-translational modifications

Isoform I is phosphorylated on Ser-600. Isoform J is phosphorylated on Ser-631.

Protein cellular localization

Cell projection, growth cone . Cytoplasmic vesicle . Cytoplasm, cytoskeleton .

Background

Conventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, and transports various cargos along microtubules toward their plus ends. The heavy chains provide the motor activity, while the light chains bind to various cargos. This gene encodes a member of the kinesin light chain family. It associates with kinesin heavy chain through an N-terminal domain, and six tetratricopeptide repeat (TPR) motifs are thought to be involved in binding of cargos such as vesicles, mitochondria, and the Golgi complex. Thus, kinesin light chains function as adapter molecules and not motors per se. Although previously named “kinesin 2”, this gene is not a member of the kinesin-2 / kinesin heavy chain subfamily of kinesin motor proteins. Extensive alternative splicing produces isoforms with different C-termini that are proposed to bind to different cargos; however, the full-length nature and/or biological validity of most of these variants have not been determined.

Note

AntibodyPlus can customize KLC1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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