Rabbit polyclonal KNG1 antibody (A1670)


Reactivity: Human,Mouse
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal KNG1 antibody (A1670)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody


BDK antibody, KNG antibody
Alpha-2-thiol proteinase inhibitor antibody|BDK antibody|BK antibody|Fitzgerald factor antibody|High molecular weight kininogen antibody|HMWK antibody|Ile-Ser-Bradykinin antibody|Kallidin I antibody|Kallidin II antibody|Kininogen 1 antibody|KNG antibody|KNG1 antibody|KNG1_HUMAN antibody|LMW antibody|Low molecular weight growth-promoting factor antibody|Low molecular weight kininogen antibody|Williams-Fitzgerald-Flaujeac factor antibody|Anti-Kininogen 1 antibody [EPR6097] (ab124737)

SCBT cat No: sc-293304|sc-14941|sc-293196|sc-15045|sc-25484|sc-15048|sc-15041|sc-15043|sc-136216|


Rabbit polyclonal KNG1 antibody

Catalogue No.



Human, Mouse


Recombinant protein of human KNG1





Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200







Molecular weight

Predicted: 72kDa/Observed: Refer to Figures


KNG1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.


KNG1 antibody was purified using affinity purification.


Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

BDK antibody, KNG antibody

Database links

Human UniProt/Swiss-Prot:P01042

Protein names


Protein function

(1) Kininogens are inhibitors of thiol proteases; (2) HMW-kininogen plays an important role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII; (3) HMW-kininogen inhibits the thrombin- and plasmin-induced aggregation of thrombocytes; (4) the active peptide bradykinin that is released from HMW-kininogen shows a variety of physiological effects: (4A) influence in smooth muscle contraction, (4B) induction of hypotension, (4C) natriuresis and diuresis, (4D) decrease in blood glucose level, (4E) it is a mediator of inflammation and causes (4E1) increase in vascular permeability, (4E2) stimulation of nociceptors (4E3) release of other mediators of inflammation (e.g. prostaglandins), (4F) it has a cardioprotective effect (directly via bradykinin action, indirectly via endothelium-derived relaxing factor action); (5) LMW-kininogen inhibits the aggregation of thrombocytes; (6) LMW-kininogen is in contrast to HMW-kininogen not involved in blood clotting.

Protein tissue specificity

Secreted in plasma. T-kinin is detected in malignant ovarian, colon and breast carcinomas, but not in benign tumors.

Protein sequence and domain

Contains 3 cystatin kininogen-type domains.

Protein post-translational modifications

Bradykinin is released from kininogen by plasma kallikrein.; Hydroxylation of Pro-383 occurs prior to the release of bradykinin.; Phosphorylated by FAM20C in the extracellular medium.; N- and O-glycosylated. O-glycosylated with core 1 or possibly core 8 glycans.

Protein cellular localization

Secreted, extracellular space.


Kininogens are inhibitors of thiol proteases. Kininogen 1 plays important role in Kinin-kallikrein system. This gene is translated into High-molecular weight kininogen (HMWK) and low-molecular weight kininogen (LMWK) after alternative splicing. HMWK is produced by the liver together with prekallikrein. It acts mainly as a cofactor on coagulation and inflammation, and has no intrinsic catalytic activity. LMWK is produced locally by numerous tissues, and secreted together with tissue kallikrein. 11926-1-AP was generated against N-terminal 300 aa of HMW kininogen. It can bind both HMW and LMW kiniogen.


AntibodyPlus can customize KNG1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody


ABclonal Inc.


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