Rabbit polyclonal KRT19 antibody (A0247)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal KRT19 antibody (A0247)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal KRT19 antibody.

Alternative names:

Check alternative names for the antibody

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KRT19 antibody, K1CS antibody, CK19 antibody, K19 antibody, CK 19 antibody, Cytokeratin 19 antibody
40 kDa keratin intermediate filament antibody|CK 19 antibody|CK-19 antibody|CK19 antibody|Cytokeratin 19 antibody|Cytokeratin-19 antibody|K19 antibody|K1C19_HUMAN antibody|K1CS antibody|Keratin 19 antibody|Keratin type I 40 kD antibody|Keratin type I 40kD antibody|Keratin type I cytoskeletal 19 antibody|Keratin, type I cytoskeletal 19 antibody|Keratin, type I, 40 kd antibody|Keratin-19 antibody|KRT19 antibody|MGC15366 antibody|Anti-Cytokeratin 19 antibody [A53-B/A2] (ab7754)

SCBT cat No: sc-376126|sc-6278|sc-374192|sc-53257|sc-53258|sc-33110|sc-374386|sc-25724|sc-33111|sc-33119|sc-53003|

Name

Rabbit polyclonal KRT19 antibody

Catalogue No.

A0247

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human KRT19

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 40kDa/Observed: Refer to Figures

Formulation

KRT19 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

KRT19 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

KRT19 antibody, K1CS antibody, CK19 antibody, K19 antibody, CK 19 antibody, Cytokeratin 19 antibody

Database links

Human UniProt/Swiss-Prot:P08727

Protein names

KRT19, K1CS, CK19, K19, CK 19, Cytokeratin 19

Protein function

Involved in the organization of myofibers. Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.

Protein tissue specificity

Expressed in a defined zone of basal keratinocytes in the deep outer root sheath of hair follicles. Also observed in sweat gland and mammary gland ductal and secretory cells, bile ducts, gastrointestinal tract, bladder urothelium, oral epithelia, esophagus, ectocervical epithelium (at protein level). Expressed in epidermal basal cells, in nipple epidermis and a defined region of the hair follicle. Also seen in a subset of vascular wall cells in both the veins and artery of human umbilical cord, and in umbilical cord vascular smooth muscle. Observed in muscle fibers accumulating in the costameres of myoplasm at the sarcolemma in structures that contain dystrophin and spectrin.

Protein sequence and domain

This keratin differs from all other IF proteins in lacking the C-terminal tail domain.Belongs to the intermediate filament family.

Background

Keratins (cytokeratins) are intermediate filament proteins that are mainly expressed in epithelial cells. Keratin heterodimers composed of an acidic keratin (or type I keratin, keratins 9 to 23) and a basic keratin (or type II keratin, keratins 1 to 8) assemble to form filaments (1,2). Keratin isoforms demonstrate tissue- and differentiation-specific profiles that make them useful as biomarkers (1). Mutations in keratin genes are associated with skin disorders, liver and pancreatic diseases, and inflammatory intestinal diseases (3-6).Keratin 7 and Keratin 19 have been shown to be present in hepatic and pancreatic progenitor/stem cells (7,8).

Research area

All research areas>Structural Proteins>Cytokeratin
(View all antibody categories related to Structural Proteins)

Note

AntibodyPlus can customize KRT19 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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