Rabbit Polyclonal KRT2 antibody (A10375)

$99.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit Polyclonal KRT2 antibody (A10375)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:500 – 1:2000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

Expand

K2e antibody; KRTE antibody; CK-2e antibody; KRT2A antibody; KRT2E antibody;
CK 2e antibody|Cytokeratin-2e antibody|Epithelial keratin-2e antibody|K2e antibody|Keratin type II cytoskeletal 2 epidermal antibody|Keratin-2 epidermis antibody|KRT2 antibody|KRT2A antibody|KRT2E antibody|Type-II keratin Kb2 antibody|Anti-Cytokeratin 2e antibody [Ks2.342.7.1] (ab19122)

SCBT cat No: sc-58731|sc-49179|

Name

Rabbit Polyclonal KRT2 antibody

Catalogue No.

A10375

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human KRT2

Host

Rabbit

Applications

WB

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

70kDa

Formulation

KRT2 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

Affinity purification

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

K2e antibody; KRTE antibody; CK-2e antibody; KRT2A antibody; KRT2E antibody;

Protein names

K2e; KRTE; CK-2e; KRT2A; KRT2E;

Protein function

Probably contributes to terminal cornification. Associated with keratinocyte activation, proliferation and keratinization.

Protein tissue specificity

Expressed in the upper spinous and granular suprabasal layers of normal adult epidermal tissues from most body sites including thigh, breast nipple, foot sole, penile shaft and axilla. Not present in foreskin, squamous metaplasias and carcinomas. Expression in hypertrophic and keloid scars begins in the deepest suprabasal layer. Weakly expressed in normal gingiva and tongue, however expression is induced in benign keratoses of lingual mucosa and in mild-to-moderate oral dysplasia with orthokeratinization.

Protein sequence and domain

Belongs to the intermediate filament family.

Background

The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is expressed largely in the upper spinous layer of epidermal keratinocytes and mutations in this gene have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.

Note

AntibodyPlus can customize KRT2 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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