Rabbit polyclonal KRT20 antibody (A0248)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

Clear
-$50 as credit for submitting review for primary antibody
Shipping notice:
Product will be delivered in 6 to 8 Business Days

Rabbit polyclonal KRT20 antibody (A0248)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal KRT20 antibody.

Alternative names:

Check alternative names for the antibody

Expand

KRT20 antibody,K20 antibody,Cytokeratin 20 antibody,KRT21 antibody,CK 20 antibody,Protein IT antibody
CD20 antibody|CK 20 antibody|CK-20 antibody|CK20 antibody|Cytokeratin-20 antibody|Cytokeratin20 antibody|K1C20_HUMAN antibody|K20 antibody|KA20 antibody|Keratin 20 antibody|keratin 20, type I antibody|keratin 21, rat, homolog of antibody|Keratin antibody|Keratin type I cytoskeletal 20 antibody|Keratin-20 antibody|Keratin20 antibody|KRT 20 antibody|KRT 21 antibody|KRT20 antibody|KRT21 antibody|MGC35423 antibody|OTTHUMP00000164518 antibody|Protein IT antibody|type I cytoskeletal 20 antibody|Anti-Cytokeratin 20 antibody [EPR1622Y] (ab76126)

SCBT cat No: sc-271183|sc-17113|sc-25725|sc-52320|sc-17112|sc-56522|sc-100927|sc-365892|sc-58731|sc-49179|

Name

Rabbit polyclonal KRT20 antibody

Catalogue No.

A0248

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human KRT20

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 48kDa/Observed: Refer to Figures

Formulation

KRT20 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

KRT20 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

KRT20 antibody,K20 antibody,Cytokeratin 20 antibody,KRT21 antibody,CK 20 antibody,Protein IT antibody

Database links

Human UniProt/Swiss-Prot:P35900

Protein names

KRT20,K20,Cytokeratin 20,KRT21,CK 20,Protein IT

Protein function

Plays a significant role in maintaining keratin filament organization in intestinal epithelia. When phosphorylated, plays a role in the secretion of mucin in the small intestine (By similarity).

Protein tissue specificity

Expressed predominantly in the intestinal epithelium. Expressed in luminal cells of colonic mucosa. Also expressed in the Merkel cells of keratinized oral mucosa; specifically at the tips of some rete ridges of the gingival mucosa, in the basal layer of the palatal mucosa and in the taste buds of lingual mucosa.

Protein sequence and domain

Belongs to the intermediate filament family.

Protein post-translational modifications

Hyperphosphorylation at Ser-13 occurs during the early stages of apoptosis but becomes less prominent during the later stages. Phosphorylation at Ser-13 also increases in response to stress brought on by cell injury (By similarity).; Proteolytically cleaved by caspases during apoptosis. Cleavage occurs at Asp-228.

Protein cellular localization

Cytoplasm .

Background

Intermediate-sized filament (IF) protein designated cytokeratin (CK) 20 is a major cellular protein of mature enterocytes and goblet cells commonly found in mucosal epithelium of the mammalian gastrointestinal tract (1). Results strongly suggest that transcriptional regulation of keratin genes in the intestinal epithelium occurs at the level of both immature and terminally differentiated epithelial cells, and is tightly regulated during both fetal development and crypt-to-villus differentiation of the intestinal epithelium (2). CK20 has recently been reported to be useful to distinguish between primary and metastatic lung adenocarcinoma. CK20 expression was significantly more prevalent in adenocarcinoma that originated in the GI tract than that of pulmonary or breast origin (3).

Research area

All research areas>Structural Proteins>Cytokeratin
(View all antibody categories related to Structural Proteins)

Note

AntibodyPlus can customize KRT20 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

Reviews


There are no reviews yet.

Only logged in customers who have purchased this product may leave a review

There are no reviews for this product yet.
By submitting a review, get following benefits:

1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!

view database submit reviews

There is no extra validation for this product yet.
Check other extra validated antibodies below:



Welcome to AntibodyPlus!