Rabbit polyclonal KRT8 antibody (A1024)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,ICC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal KRT8 antibody (A1024)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,ICC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 ICC 1:50 – 1:100 IF 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal KRT8 antibody.

Alternative names:

Check alternative names for the antibody

Expand

KRT8 antibody,CARD2 antibody,CK8 antibody,CYK8 antibody,K2C8 antibody,K8 antibody,KO antibody
CARD2 antibody|Cell proliferation inducing gene 46 protein antibody|Cell proliferation inducing protein 46 antibody|CK 8 antibody|CK-8 antibody|CK18 antibody|CK8 antibody|CYK18 antibody|CYK8 antibody|Cytokeratin 18 antibody|Cytokeratin 8 antibody|Cytokeratin-8 antibody|K18 antibody|K2C8 antibody|K2C8_HUMAN antibody|K8 antibody|Keratin 18 antibody|Keratin 8 antibody|Keratin antibody|Keratin type I cytoskeletal 18 antibody|keratin type II cytoskeletal 8 antibody|Keratin-8 antibody|KO antibody|KRT18 antibody|KRT8 antibody|type II cytoskeletal 8 antibody|Type-II keratin Kb8 antibody|Anti-Cytokeratin 8+18 antibody [EP1628Y] (ab53280)

SCBT cat No: sc-130312|sc-58736|sc-73480|sc-58737|sc-374275|sc-8020|sc-374274|sc-374027|sc-134484|sc-101459|sc-53266|sc-52324|

Name

Rabbit polyclonal KRT8 antibody

Catalogue No.

A1024

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human KRT8

Host

Rabbit

Applications

WB, IHC, ICC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
ICC 1:50 – 1:100
IF 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 54kDa/Observed: Refer to Figures

Formulation

KRT8 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

KRT8 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

KRT8 antibody,CARD2 antibody,CK8 antibody,CYK8 antibody,K2C8 antibody,K8 antibody,KO antibody

Database links

Human UniProt/Swiss-Prot:P05787

Protein names

KRT8,CARD2,CK8,CYK8,K2C8,K8,KO

Protein function

Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.

Protein tissue specificity

Observed in muscle fibers accumulating in the costameres of myoplasm at the sarcolemma membrane in structures that contain dystrophin and spectrin. Expressed in gingival mucosa and hard palate of the oral cavity.

Protein sequence and domain

Belongs to the intermediate filament family.

Protein post-translational modifications

Phosphorylation on serine residues is enhanced during EGF stimulation and mitosis. Ser-74 phosphorylation plays an important role in keratin filament reorganization.; O-glycosylated. O-GlcNAcylation at multiple sites increases solubility, and decreases stability by inducing proteasomal degradation.; O-glycosylated (O-GlcNAcylated), in a cell cycle-dependent manner.

Protein cellular localization

Cytoplasm . Nucleus, nucleoplasm . Nucleus matrix .

Background

Keratins (cytokeratins) are intermediate filament proteins that are mainly expressed in epithelial cells. Keratin heterodimers composed of an acidic keratin (or type I keratin, keratins 9 to 23) and a basic keratin (or type II keratin, keratins 1 to 8) assemble to form filaments (1,2). Keratin isoforms demonstrate tissue- and differentiation-specific profiles that make them useful as biomarkers (1). Research studies have shown that mutations in keratin genes are associated with skin disorders, liver and pancreatic diseases, and inflammatory intestinal diseases (3-6).

Research area

All research areas>Structural Proteins>Cytokeratin
(View all antibody categories related to Structural Proteins)

Note

AntibodyPlus can customize KRT8 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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