Rabbit polyclonal L1CAM antibody (A8555)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal L1CAM antibody (A8555)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:500 – 1:2000

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal L1CAM antibody.

Alternative names:

Check alternative names for the antibody

Expand

S10 antibody, HSAS antibody, MASA antibody, MIC5 antibody, SPG1 antibody, CAML1 antibody, CD171 antibody, HSAS1 antibody, N-CAML1 antibody, NCAM-L1 antibody, N-CAM-L1 antibody
Antigen identified by monoclonal antibody R1 antibody|CAML1 antibody|CD171 antibody|CD171 antigen antibody|HSAS antibody|HSAS1 antibody|Hyd antibody|L1 antibody|L1 cell adhesion molecule antibody|L1-NCAM antibody|L1cam antibody|L1CAM_HUMAN antibody|MASA antibody|MIC5 antibody|N CAML1 antibody|N-CAM-L1 antibody|NCAM-L1 antibody|NCAML1 antibody|Nerve-growth factor-inducible large external glycoprotein antibody|Neural cell adhesion molecule L1 antibody|NILE antibody|OTTHUMP00000025992 antibody|S10 antibody|SPG1 antibody|Anti-L1CAM antibody [2C2] (ab24345)

SCBT cat No: sc-71653|sc-33686|sc-59868|sc-514360|sc-1508|sc-374046|sc-15326|sc-8305|sc-31034|sc-31032|sc-53386|sc-53387|

Name

Rabbit polyclonal L1CAM antibody

Catalogue No.

A8555

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human L1CAM

Host

Rabbit

Applications

WB

Recommended dilution

WB 1:500 – 1:2000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 140kDa/Observed: Refer to figures

Formulation

L1CAM antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

L1CAM antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

S10 antibody, HSAS antibody, MASA antibody, MIC5 antibody, SPG1 antibody, CAML1 antibody, CD171 antibody, HSAS1 antibody, N-CAML1 antibody, NCAM-L1 antibody, N-CAM-L1 antibody

Database links

Human UniProt/Swiss-Prot:P32004

Protein names

S10, HSAS, MASA, MIC5, SPG1, CAML1, CD171, HSAS1, N-CAML1, NCAM-L1, N-CAM-L1

Protein function

Cell adhesion molecule with an important role in the development of the nervous system. Involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. Binds to axonin on neurons.

Protein sequence and domain

Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.; Contains 5 fibronectin type-III domains.; Contains 6 Ig-like C2-type (immunoglobulin-like) domains.

Protein cellular localization

Cell membrane ; Single-pass type I membrane protein . Cell projection, growth cone . Note: Colocalized with SHTN1 in close apposition with actin filaments in filopodia and lamellipodia of axonalne growth cones of hippocampal neurons.

Background

The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of this gene results in multiple transcript variants, some of which include an alternate exon that is considered to be specific to neurons.

Research area

All research areas>Cell Adhesion Proteins>NCAM
(View all antibody categories related to Cell Adhesion Proteins)

Note

AntibodyPlus can customize L1CAM antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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