Rabbit polyclonal LAMP2 antibody (A1961)

$69.00$259.00

Reactivity: Human
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

Clear
-$50 as credit for submitting review for primary antibody
Shipping notice:
Product will be delivered in 6 to 8 Business Days

Rabbit polyclonal LAMP2 antibody (A1961)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal LAMP2 antibody.

Alternative names:

Check alternative names for the antibody

Expand

LAMPB antibody, CD107b antibody, LAMP-2 antibody, LGP110 antibody
CD107 antigen-like family member B antibody|CD107b antibody|LAMP 2 antibody|LAMP 2C antibody|LAMP-2 antibody|LAMP2 antibody|LAMP2_HUMAN antibody|LAMPB antibody|LGP110 antibody|Lysosomal associated membrane protein 2 antibody|Lysosome associated membrane protein 2 antibody|Lysosome-associated membrane glycoprotein 2 antibody|Lysosome-associated membrane protein 2 antibody|MAC3 antibody|Anti-LAMP2 antibody [H4B4] (ab25631)

SCBT cat No: sc-71492|sc-34243|sc-20004|sc-8100|sc-34244|sc-47749|sc-5571|

Name

Rabbit polyclonal LAMP2 antibody

Catalogue No.

A1961

Reactivity

Human

Immunogen

Recombinant protein of human LAMP2

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 45kDa/Observed: Refer to Figures

Formulation

LAMP2 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

LAMP2 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

LAMPB antibody, CD107b antibody, LAMP-2 antibody, LGP110 antibody

Database links

Human UniProt/Swiss-Prot:P13473

Protein names

LAMPB, CD107b, LAMP-2, LGP110

Protein function

Implicated in tumor cell metastasis. May function in protection of the lysosomal membrane from autodigestion, maintenance of the acidic environment of the lysosome, adhesion when expressed on the cell surface (plasma membrane), and inter- and intracellular signal transduction. Protects cells from the toxic effects of methylating mutagens.

Protein tissue specificity

Isoform LAMP-2A is highly expressed in placenta, lung and liver, less in kidney and pancreas, low in brain and skeletal muscle. Isoform LAMP-2B is highly expressed in skeletal muscle, less in brain, placenta, lung, kidney and pancreas, very low in liver.

Protein sequence and domain

Belongs to the LAMP family.

Protein post-translational modifications

O- and N-glycosylated; some of the 16 N-linked glycans are polylactosaminoglycans.

Protein cellular localization

Cell membrane ; Single-pass type I membrane protein . Endosome membrane ; Single-pass type I membrane protein . Lysosome membrane ; Single-pass type I membrane protein . Note: This protein shuttles between lysosomes, endosomes, and the plasma membrane.

Background

Lysosomal-associated membrane protein 2 (LAMP2, synonyms: LAMPB, CD107b) is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. LAMP2 may plays a role in tumor cell metastasis. It may also functions in the protection, maintenance, and adhesion of the lysosome.Prior to posttranslational modification, Lysosome Associated Membrane Protein 2 (LAMP2) is a ~45 kDa polypeptide. Mature, functional LAMP2 is extensively glycosylated with a variety of different N linked and O linked oligosaccharides with a total molecular weight of ~100-110 kDa.

Research area

All research areas>Lymphocyte Signaling>LAMP
(View all antibody categories related to Lymphocyte Signaling)

Note

AntibodyPlus can customize LAMP2 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

Reviews


There are no reviews yet.

Only logged in customers who have purchased this product may leave a review

There are no reviews for this product yet.
By submitting a review, get following benefits:

1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!

view database submit reviews

There is no extra validation for this product yet.
Check other extra validated antibodies below:



Welcome to AntibodyPlus!