Rabbit polyclonal LDB3 antibody (A7462)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal LDB3 antibody (A7462)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

Expand

MFM4 antibody, ZASP antibody, CMD1C antibody, CMPD3 antibody, LVNC3 antibody, CYPHER antibody, LDB3Z1 antibody, LDB3Z4 antibody, ORACLE antibody, PDLIM6 antibody
CMD1C antibody|CYPHER antibody|HGNC:15710 antibody|KIAA01613 antibody|KIAA0613 antibody|Ldb3 antibody|LDB3_HUMAN antibody|LDB3Z1 antibody|LDB3Z4 antibody|LIM domain binding 3 antibody|LIM domain binding protein 3 antibody|LIM domain-binding protein 3 antibody|LVNC3 antibody|ORACLE antibody|PDLIM6 antibody|PDZ and LIM domain 6 antibody|Protein cypher antibody|Z band alternatively spliced PDZ motif antibody|Z band alternatively spliced PDZ motif protein antibody|Z-band alternatively spliced PDZ-motif protein antibody|ZASP antibody|Anti-LDB3 antibody [EPR10127] (ab154183)

SCBT cat No: sc-374359|sc-82848|

Name

Rabbit polyclonal LDB3 antibody

Catalogue No.

A7462

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human LDB3

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 77kDa/Observed: Refer to figures

Formulation

LDB3 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

LDB3 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

MFM4 antibody, ZASP antibody, CMD1C antibody, CMPD3 antibody, LVNC3 antibody, CYPHER antibody, LDB3Z1 antibody, LDB3Z4 antibody, ORACLE antibody, PDLIM6 antibody

Database links

Human UniProt/Swiss-Prot:O75112

Protein names

MFM4, ZASP, CMD1C, CMPD3, LVNC3, CYPHER, LDB3Z1, LDB3Z4, ORACLE, PDLIM6

Protein function

May function as an adapter in striated muscle to couple protein kinase C-mediated signaling via its LIM domains to the cytoskeleton.

Protein tissue specificity

Expressed primarily in skeletal muscle and to a lesser extent in heart. Also detected in brain and placenta.

Protein sequence and domain

Contains 3 LIM zinc-binding domains.; Contains 1 PDZ (DHR) domain.

Protein cellular localization

Cytoplasm, perinuclear region . Cell projection, pseudopodium . Cytoplasm, cytoskeleton . Cytoplasm, myofibril, sarcomere, Z line . Note: Localized to the cytoplasm around nuclei and pseudopodia of undifferentiated cells and detected throughout the myotubes of differentiated cells. Colocalizes with ACTN2 at the Z-lines.

Background

This gene encodes a PDZ domain-containing protein. PDZ motifs are modular protein-protein interaction domains consisting of 80-120 amino acid residues. PDZ domain-containing proteins interact with each other in cytoskeletal assembly or with other proteins involved in targeting and clustering of membrane proteins. The protein encoded by this gene interacts with alpha-actinin-2 through its N-terminal PDZ domain and with protein kinase C via its C-terminal LIM domains. The LIM domain is a cysteine-rich motif defined by 50-60 amino acids containing two zinc-binding modules. This protein also interacts with all three members of the myozenin family. Mutations in this gene have been associated with myofibrillar myopathy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been identified; all isoforms have N-terminal PDZ domains while only longer isoforms (1, 2 and 5) have C-terminal LIM domains.

Note

AntibodyPlus can customize LDB3 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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