Rabbit polyclonal LEPREL1 antibody (A8068)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal LEPREL1 antibody (A8068)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal LEPREL1 antibody.

Alternative names:

Check alternative names for the antibody

Expand

MCVD antibody, MLAT4 antibody, LEPREL1 antibody
4832416N06 antibody|AW553532 antibody|Leprecan like 1 antibody|Leprecan-like protein 1 antibody|Leprel1 antibody|MCVD antibody|MLAT4 antibody|Myxoid liposarcoma-associated protein 4 antibody|P3H2 antibody|P3H2_HUMAN antibody|Prolyl 3 hydroxylase 3 antibody|Prolyl 3-hydroxylase 2 antibody|Anti-LEPREL1 antibody (ab121270)

SCBT cat No: sc-377353|sc-377096|

Name

Rabbit polyclonal LEPREL1 antibody

Catalogue No.

A8068

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant Protein of human LEPREL1

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 81kDa/Observed: Refer to figures

Formulation

LEPREL1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

LEPREL1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

MCVD antibody, MLAT4 antibody, LEPREL1 antibody

Database links

Human UniProt/Swiss-Prot:Q8IVL5

Protein names

MCVD, MLAT4, LEPREL1

Protein function

Shows prolyl 3-hydroxylase activity catalyzing the post-translational formation of 3-hydroxyproline in -Xaa-Pro-Gly-sequences in collagens, especially types II, IV and V.

Protein tissue specificity

Expressed in heart, placenta, lung, liver, skeletal muscle and kidney. Expression localized to the epithelia of bile ducts and to the sacroplasm of heart muscle and skeletal muscle. In the pancreas, localized to a subpopulation of Langerhans islet cells and in the salivary gland, expressed in acinar cells.

Protein sequence and domain

Belongs to the leprecan family.; Contains 1 Fe2OG dioxygenase domain.; Contains 4 TPR repeats.

Protein cellular localization

Endoplasmic reticulum . Golgi apparatus .

Background

This gene encodes a member of the prolyl 3-hydroxylase subfamily of 2-oxo-glutarate-dependent dioxygenases. These enzymes play a critical role in collagen chain assembly, stability and cross-linking by catalyzing post-translational 3-hydroxylation of proline residues. Mutations in this gene are associated with nonsyndromic severe myopia with cataract and vitreoretinal degeneration, and downregulation of this gene may play a role in breast cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Note

AntibodyPlus can customize LEPREL1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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