No products in the cart.
Rabbit polyclonal LIG3 antibody (A1887)
Supplier: ABclonal Inc.
Recommended applications: WB,IHC,IF
WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit polyclonal LIG3 antibody.
Check alternative names for the antibodyExpand
LIG2 antibody, LIG3 antibody
D11Wsu78e antibody|DNA ligase antibody|DNA ligase 3 antibody|DNA ligase III antibody|DNLI3_HUMAN antibody|LIG 3 antibody|LIG2 antibody|LIG3 antibody|Ligase II, DNA, ATP dependent antibody|Ligase III DNA ATP dependent antibody|MGC78176 antibody|OTTMUSP00000000875 antibody|Polydeoxyribonucleotide synthase [ATP] 3 antibody|Polydeoxyribonucleotide synthase [ATP] antibody|Polydeoxyribonucleotide synthase antibody|RP23-316C11.6 antibody|Anti-DNA Ligase III antibody [6G9] (ab587)
SCBT cat No: sc-56089|sc-135883|sc-390922|sc-292772|
Rabbit polyclonal LIG3 antibody
|Catalogue No.|| |
Human, Mouse, Rat
Recombinant protein of human LIG3
WB, IHC, IF
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
Predicted: 113kDa/Observed: Refer to Figures
LIG3 antibody was tube-contained.
LIG3 antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Alternative antibody names|| |
LIG2 antibody, LIG3 antibody
|Database links|| |
|Protein names|| |
|Protein function|| |
Isoform 3 functions as heterodimer with DNA-repair protein XRCC1 in the nucleus and can correct defective DNA strand-break repair and sister chromatid exchange following treatment with ionizing radiation and alkylating agents. Isoform 1 is targeted to mitochondria, where it functions as DNA ligase in mitochondrial base-excision DNA repair .
|Protein tissue specificity|| |
Testis, thymus, prostate and heart.
|Protein sequence and domain|| |
The PARP-type zinc finger is required for DNA ligase activity.Belongs to the ATP-dependent DNA ligase family.; Contains 1 BRCT domain.; Contains 1 PARP-type zinc finger.
|Protein cellular localization|| |
Isoform 1: Mitochondrion . Note: Contains an N-terminal mitochondrial transit peptide.; Isoform 2: Mitochondrion . Note: Contains an N-terminal mitochondrial transit peptide.; Isoform 3: Nucleus . Note: Lacks the N-terminal mitochondrial transit peptide.; Isoform 4: Nucleus . Note: Lacks the N-terminal mitochondrial transit peptide.
This gene is a member of the DNA ligase family. Each member of this family encodes a protein that catalyzes the joining of DNA ends but they each have a distinct role in DNA metabolism. The protein encoded by this gene is involved in excision repair and is located in both the mitochondria and nucleus, with translation initiation from the upstream start codon allowing for transport to the mitochondria and translation initiation from a downstream start codon allowing for transport to the nucleus. Additionally, alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
AntibodyPlus can customize LIG3 antibody according to your requirement, including bulk product size,etc. Please contact email@example.com. AntibodyPlus provides antibody trial sample for your own antibody validation.
|Product type|| |
There are no reviews for this product yet.
By submitting a review, get following benefits:
1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!
There is no extra validation for this product yet.
Check other extra validated antibodies below: