Rabbit polyclonal LIG3 antibody (A1887)


Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal LIG3 antibody (A1887)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody


LIG2 antibody, LIG3 antibody
D11Wsu78e antibody|DNA ligase antibody|DNA ligase 3 antibody|DNA ligase III antibody|DNLI3_HUMAN antibody|LIG 3 antibody|LIG2 antibody|LIG3 antibody|Ligase II, DNA, ATP dependent antibody|Ligase III DNA ATP dependent antibody|MGC78176 antibody|OTTMUSP00000000875 antibody|Polydeoxyribonucleotide synthase [ATP] 3 antibody|Polydeoxyribonucleotide synthase [ATP] antibody|Polydeoxyribonucleotide synthase antibody|RP23-316C11.6 antibody|Anti-DNA Ligase III antibody [6G9] (ab587)

SCBT cat No: sc-56089|sc-135883|sc-390922|sc-292772|


Rabbit polyclonal LIG3 antibody

Catalogue No.



Human, Mouse, Rat


Recombinant protein of human LIG3





Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:200







Molecular weight

Predicted: 113kDa/Observed: Refer to Figures


LIG3 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.


LIG3 antibody was purified using affinity purification.


Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

LIG2 antibody, LIG3 antibody

Database links

Human UniProt/Swiss-Prot:P49916

Protein names


Protein function

Isoform 3 functions as heterodimer with DNA-repair protein XRCC1 in the nucleus and can correct defective DNA strand-break repair and sister chromatid exchange following treatment with ionizing radiation and alkylating agents. Isoform 1 is targeted to mitochondria, where it functions as DNA ligase in mitochondrial base-excision DNA repair .

Protein tissue specificity

Testis, thymus, prostate and heart.

Protein sequence and domain

The PARP-type zinc finger is required for DNA ligase activity.Belongs to the ATP-dependent DNA ligase family.; Contains 1 BRCT domain.; Contains 1 PARP-type zinc finger.

Protein cellular localization

Isoform 1: Mitochondrion . Note: Contains an N-terminal mitochondrial transit peptide.; Isoform 2: Mitochondrion . Note: Contains an N-terminal mitochondrial transit peptide.; Isoform 3: Nucleus . Note: Lacks the N-terminal mitochondrial transit peptide.; Isoform 4: Nucleus . Note: Lacks the N-terminal mitochondrial transit peptide.


This gene is a member of the DNA ligase family. Each member of this family encodes a protein that catalyzes the joining of DNA ends but they each have a distinct role in DNA metabolism. The protein encoded by this gene is involved in excision repair and is located in both the mitochondria and nucleus, with translation initiation from the upstream start codon allowing for transport to the mitochondria and translation initiation from a downstream start codon allowing for transport to the nucleus. Additionally, alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

Research area

All research areas>Tumor Suppressor/Apoptosis>DNA Ligase
(View all antibody categories related to Tumor Suppressor/Apoptosis)


AntibodyPlus can customize LIG3 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody


ABclonal Inc.


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