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Rabbit polyclonal LIMS1 antibody (A6384)
$69.00–$259.00
Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.
Rabbit polyclonal LIMS1 antibody (A6384)
Supplier: ABclonal Inc.
Recommended applications: WB,IHC,IF
Recommended dilution:
WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:100
Recommended protocols: check protocols
Image descriptions:
Click or hover above images to see image description for Rabbit polyclonal LIMS1 antibody.
Alternative names:
Check alternative names for the antibody
ExpandPINCH antibody, PINCH1 antibody, PINCH-1 antibody
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SCBT cat No: sc-136299|sc-393133|sc-393151|sc-47914|sc-67177|
Name | Rabbit polyclonal LIMS1 antibody |
---|---|
Catalogue No. | A6384 |
Reactivity | Human, Mouse, Rat |
Immunogen | Recombinant protein of human LIMS1 |
Host | Rabbit |
Applications | WB, IHC, IF |
Recommended dilution | WB 1:500 – 1:2000 |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Molecular weight | Predicted: 37kDa/Observed: Refer to Figures |
Formulation | LIMS1 antibody was tube-contained. |
Purification | LIMS1 antibody was purified using affinity purification. |
Storage | Store at -20 Celsius degree. Avoid freeze / thaw cycles. |
Alternative antibody names | PINCH antibody, PINCH1 antibody, PINCH-1 antibody |
Database links | Human UniProt/Swiss-Prot:P48059 |
Protein names | PINCH, PINCH1, PINCH-1 |
Protein function | Adapter protein in a cytoplasmic complex linking beta-integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. Involved in the regulation of cell survival, cell proliferation and cell differentiation. |
Protein tissue specificity | Expressed in most tissues except in the brain. |
Protein sequence and domain | Contains 5 LIM zinc-binding domains. |
Protein cellular localization | Cell junction, focal adhesion. Cell membrane; Peripheral membrane protein; Cytoplasmic side. |
Background | The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene. |
Research area | All research areas>Signaling Intermediates>Pinch |
Note | AntibodyPlus can customize LIMS1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation. |
Product type | Primary antibody |
Supplier | ABclonal Inc. |
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