Rabbit polyclonal LIPA antibody (A6385)

$69.00$259.00

Reactivity: Human
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal LIPA antibody (A6385)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal LIPA antibody.

Alternative names:

Check alternative names for the antibody

Expand

LAL antibody, CESD antibody
Acid cholesteryl ester hydrolase antibody|CESD antibody|cholesterol ester hydrolase antibody|cholesterol ester storage disease antibody|Cholesteryl esterase antibody|Hydrolase deficiency antibody|LAL antibody|LAL deficiency cholesterol ester antibody|LICH_HUMAN antibody|lipA antibody|LIPA deficiency antibody|Lipase A antibody|lipase A, lysosomal acid, cholesterol esterase antibody|lysosomal acid lipase antibody|lysosomal acid lipase deficiency antibody|Lysosomal acid lipase/cholesteryl ester hydrolase antibody|Sterol esterase antibody|Anti-Lysosomal acid lipase antibody (ab73445)

SCBT cat No: sc-58374|

Name

Rabbit polyclonal LIPA antibody

Catalogue No.

A6385

Reactivity

Human

Immunogen

Recombinant protein of human LIPA

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 45kDa/Observed: Refer to figures

Formulation

LIPA antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

LIPA antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

LAL antibody, CESD antibody

Database links

Human UniProt/Swiss-Prot:P38571

Protein names

LAL, CESD

Protein function

Crucial for the intracellular hydrolysis of cholesteryl esters and triglycerides that have been internalized via receptor-mediated endocytosis of lipoprotein particles. Important in mediating the effect of LDL (low density lipoprotein) uptake on suppression of hydroxymethylglutaryl-CoA reductase and activation of endogenous cellular cholesteryl ester formation.

Protein sequence and domain

Belongs to the AB hydrolase superfamily. Lipase family.

Protein cellular localization

Lysosome.

Background

This gene encodes lipase A, the lysosomal acid lipase (also known as cholesterol ester hydrolase). This enzyme functions in the lysosome to catalyze the hydrolysis of cholesteryl esters and triglycerides. Mutations in this gene can result in Wolman disease and cholesteryl ester storage disease. Alternatively spliced transcript variants have been found for this gene.

Research area

All research areas>Synthesis and Degradation>LAL
(View all antibody categories related to Synthesis and Degradation)

Note

AntibodyPlus can customize LIPA antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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