Rabbit polyclonal LITAF antibody (A5469)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal LITAF antibody (A5469)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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PIG7 antibody, SIMPLE antibody, TP53I7 antibody
Lipopolysaccharide induced TNF alpha factor antibody|CMT1C antibody|FLJ38636 antibody|Lipopolysaccharide induced TNF alpha factor antibody|Lipopolysaccharide induced TNF factor antibody|Lipopolysaccharide induced tumor necrosis factor alpha factor antibody|Lipopolysaccharide-induced tumor necrosis factor-alpha factor antibody|LITAF antibody|LITAF_HUMAN antibody|LPS induced TNF alpha factor antibody|LPS-induced TNF-alpha factor antibody|MGC116698 antibody|MGC116700 antibody|MGC116701 antibody|MGC125274 antibody|MGC125275 antibody|MGC125276 antibody|p53 induced gene 7 protein antibody|p53-induced gene 7 protein antibody|PIG 7 antibody|PIG7 antibody|SIMPLE antibody|Small integral membrane protein of lysosome/late endosome antibody|TP53I7 antibody|Tumor protein p53 inducible protein 7 antibody|Anti-LITAF antibody (ab187533)

SCBT cat No: sc-135974|sc-166719|sc-166546|sc-66945|

Name

Rabbit polyclonal LITAF antibody

Catalogue No.

A5469

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human LITAF

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 17kDa/Observed: Refer to Figures

Formulation

LITAF antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

LITAF antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

PIG7 antibody, SIMPLE antibody, TP53I7 antibody

Database links

Human UniProt/Swiss-Prot:Q99732

Protein names

PIG7, SIMPLE, TP53I7

Protein function

Probable role in regulating transcription of specific genes. May regulate through NFKB1 the expression of the CCL2/MCP-1 chemokine. May play a role in tumor necrosis factor alpha (TNF-alpha) gene expression.

Protein tissue specificity

Ubiquitously and abundantly expressed. Expressed predominantly in the placenta, peripheral blood leukocytes, lymph nodes and spleen.

Protein sequence and domain

The WW-binding motif mediates interaction with WWOX and, probably NEDD4.Belongs to the CDIP1/LITAF family.

Protein cellular localization

Lysosome membrane ; Peripheral membrane protein ; Cytoplasmic side . Note: Associated with membranes of lysosomes.

Background

Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of this gene is induced by tumor suppresor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Paget’s disease (EMPD). Multiple alternatively spliced transcript variants have been found for this gene.

Note

AntibodyPlus can customize LITAF antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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