Rabbit polyclonal LLGL2 antibody (A8099)


Reactivity: Human,Mouse
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal LLGL2 antibody (A8099)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:100 – 1:200

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody


HGL antibody, LGL2 antibody, Hugl-2 antibody

SCBT cat No:


Rabbit polyclonal LLGL2 antibody

Catalogue No.



Human, Mouse


A synthetic peptide of human LLGL2





Recommended dilution

WB 1:500 – 1:2000
IHC 1:100 – 1:200







Molecular weight

Predicted: 113kDa/Observed: Refer to figures


LLGL2 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.


LLGL2 antibody was purified using affinity purification.


Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

HGL antibody, LGL2 antibody, Hugl-2 antibody

Database links

Human UniProt/Swiss-Prot:Q3TJ91

Protein names

HGL, LGL2, Hugl-2

Protein function

Part of a complex with GPSM2/LGN, PRKCI/aPKC and PARD6B/Par-6, which may ensure the correct organization and orientation of bipolar spindles for normal cell division. This complex plays roles in the initial phase of the establishment of epithelial cell polarity (By similarity).

Protein sequence and domain

Belongs to the WD repeat L(2)GL family.; Contains 14 WD repeats.

Protein post-translational modifications

Phosphorylated at Ser-653 by PRKCI. Phosphorylation is enhanced during cell polarization induced by calcium. Phosphorylation may occur during the cell-cell contact-induced cell polarization and may contribute to the segregation of LLGL2 from the PRKCI/aPKC and PARD6B/Par-6 complex (By similarity).

Protein cellular localization

Cytoplasm . Note: Localized in the perinuclear structure and faintly at the cell-cell contacts sites in the interphase. Localized at the cell periphery during metaphase. Cortical localization in mitotic cells (By similarity).


The lethal (2) giant larvae protein of Drosophila plays a role in asymmetric cell division, epithelial cell polarity, and cell migration. This human gene encodes a protein similar to lethal (2) giant larvae of Drosophila. In fly, the protein’s ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells. Alternative splicing results in multiple transcript variants encoding different isoforms.


AntibodyPlus can customize LLGL2 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody


ABclonal Inc.


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