Rabbit polyclonal LMNB1 antibody (A1910)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal LMNB1 antibody (A1910)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

Expand

LMN antibody, ADLD antibody, LMN2 antibody, LMNB antibody
ADLD antibody|CMD1A antibody|CMT2B1 antibody|Lamin A/C antibody|Lamin B1 antibody|Lamin B2 antibody|LMN2 antibody|LMNA antibody|LMNB1 antibody|LMNB2 antibody|Anti-Lamin B1 antibody – Nuclear Envelope Marker (ab16048)

SCBT cat No: sc-6216|sc-6217|sc-160482|sc-56143|sc-56144|sc-377000|sc-374015|sc-365214|sc-365962|sc-377001|sc-373918|sc-20682|sc-30264|

Name

Rabbit polyclonal LMNB1 antibody

Catalogue No.

A1910

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human LMNB1

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 66kDa/Observed: Refer to Figures

Formulation

LMNB1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

LMNB1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

LMN antibody, ADLD antibody, LMN2 antibody, LMNB antibody

Database links

Human UniProt/Swiss-Prot:P20700

Protein names

LMN, ADLD, LMN2, LMNB

Protein function

Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin.

Protein sequence and domain

Belongs to the intermediate filament family.; Contains 1 LTD domain.

Protein post-translational modifications

B-type lamins undergo a series of modifications, such as farnesylation and phosphorylation. Increased phosphorylation of the lamins occurs before envelope disintegration and probably plays a role in regulating lamin associations.

Protein cellular localization

Nucleus inner membrane; Lipid-anchor; Nucleoplasmic side.

Background

The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. Alternative splicing results in transcript variants and a duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD).

Research area

All research areas>Tumor Suppressor/Apoptosis>Lamin
(View all antibody categories related to Tumor Suppressor/Apoptosis)

Note

AntibodyPlus can customize LMNB1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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