Rabbit polyclonal M6PR antibody (A6296)

$69.00$259.00

Reactivity: Human,Mouse
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal M6PR antibody (A6296)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal M6PR antibody.

Alternative names:

Check alternative names for the antibody

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SMPR antibody, MPR46 antibody, CD-MPR antibody, MPR 46 antibody, MPR-46 antibody
46 kDa mannose 6 phosphate receptor antibody|46 kDa mannose 6-phosphate receptor antibody|Cation dependent mannose 6 phosphate receptor antibody|Cation dependent mannose 6 phosphate receptor precursor antibody|Cation-dependent mannose-6-phosphate receptor antibody|CD Man 6 P receptor antibody|CD Man-6-P receptor antibody|CD MPR antibody|CD-M6PR antibody|CD-MPR antibody|FLJ32994 antibody|M6pr antibody|M6PR protein antibody|Man6PR antibody|Mannose 6 phosphate receptor (cation dependent) antibody|Mannose 6 phosphate receptor antibody|MPR 46 antibody|MPR46 antibody|MPRD antibody|MPRD_HUMAN antibody|Mr 46,000 Man6PR antibody|Small mannose 6 phosphate receptor antibody|SMPR antibody|Anti-M6PR (cation dependent) antibody [EPR7691] (ab134153)

SCBT cat No: sc-66826|sc-365196|sc-34575|

Name

Rabbit polyclonal M6PR antibody

Catalogue No.

A6296

Reactivity

Human, Mouse

Immunogen

Recombinant protein of human M6PR

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 31kDa/Observed: Refer to figures

Formulation

M6PR antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

M6PR antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

SMPR antibody, MPR46 antibody, CD-MPR antibody, MPR 46 antibody, MPR-46 antibody

Database links

Human UniProt/Swiss-Prot:P20645

Protein names

SMPR, MPR46, CD-MPR, MPR 46, MPR-46

Protein function

Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex.

Protein sequence and domain

The extracellular domain is homologous to the repeating units (of approximately 147 AA) of the cation-independent mannose 6-phosphate receptor.

Protein cellular localization

Lysosome membrane; Single-pass type I membrane protein.

Background

This gene encodes a member of the P-type lectin family. P-type lectins play a critical role in lysosome function through the specific transport of mannose-6-phosphate-containing acid hydrolases from the Golgi complex to lysosomes. The encoded protein functions as a homodimer and requires divalent cations for ligand binding. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome X.

Note

AntibodyPlus can customize M6PR antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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