Rabbit polyclonal MAD2L2 antibody (A9861)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal MAD2L2 antibody (A9861)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:500 – 1:2000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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Homolog of REV7 S cerevisiae antibody|hREV7 antibody|MAD2 (mitotic arrest deficient yeast, homolog) like 2 antibody|MAD2 homolog antibody|MAD2 like 2 antibody|MAD2 mitotic arrest deficient like 2 antibody|MAD2-like protein 2 antibody|MAD2B antibody|Mad2l2 antibody|MD2L2_HUMAN antibody|Mitotic Arrest Deficient 2 L2 antibody|Mitotic arrest deficient 2-like protein 2 antibody|Mitotic arrest deficient homolog like 2 antibody|Mitotic arrest deficient like 2 (yeast) antibody|Mitotic arrest deficient yeast homolog antibody|Mitotic spindle assembly checkpoint protein MAD2B antibody|Polymerase (DNA directed) zeta 2 accessory subunit antibody|POLZ2 antibody|REV 7 antibody|REV7 antibody|REV7 homolog antibody|Weakly similar to Mitotic MAD2 protein (S cerevisiae) antibody|Anti-Mad2L2 antibody [EPR13657] (ab180579)

SCBT cat No: sc-135977|sc-27731|sc-377367|

Name

Rabbit polyclonal MAD2L2 antibody

Catalogue No.

A9861

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human MAD2L2

Host

Rabbit

Applications

WB

Recommended dilution

WB 1:500 – 1:2000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 24kDa/Observed: Refer to figures

Formulation

MAD2L2 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

MAD2L2 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Database links

Human UniProt/Swiss-Prot:Q9UI95

Protein function

Adapter protein able to interact with different proteins and involved in different biological processes. Mediates the interaction between the error-prone DNA polymerase zeta catalytic subunit REV3L and the inserter polymerase REV1, thereby mediating the second polymerase switching in translesion DNA synthesis. Translesion DNA synthesis releases the replication blockade of replicative polymerases, stalled in presence of DNA lesions. May also regulate another aspect of cellular response to DNA damage through regulation of the JNK-mediated phosphorylation and activation of the transcriptional activator ELK1. Inhibits the FZR1- and probably CDC20-mediated activation of the anaphase promoting complex APC thereby regulating progression through the cell cycle. Regulates TCF7L2-mediated gene transcription and may play a role in epithelial-mesenchymal transdifferentiation.

Protein tissue specificity

Ubiquitously expressed.

Protein sequence and domain

Contains 1 HORMA domain.

Protein cellular localization

Nucleus. Cytoplasm, cytoskeleton, spindle. Cytoplasm.

Research area

All research areas>Cell Cycle Proteins>MAD
(View all antibody categories related to Cell Cycle Proteins)

Note

AntibodyPlus can customize MAD2L2 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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