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Rabbit polyclonal MAD2L2 antibody (A9861)
Supplier: ABclonal Inc.
Recommended applications: WB
WB 1:500 – 1:2000
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit polyclonal MAD2L2 antibody.
Check alternative names for the antibodyExpand
Homolog of REV7 S cerevisiae antibody|hREV7 antibody|MAD2 (mitotic arrest deficient yeast, homolog) like 2 antibody|MAD2 homolog antibody|MAD2 like 2 antibody|MAD2 mitotic arrest deficient like 2 antibody|MAD2-like protein 2 antibody|MAD2B antibody|Mad2l2 antibody|MD2L2_HUMAN antibody|Mitotic Arrest Deficient 2 L2 antibody|Mitotic arrest deficient 2-like protein 2 antibody|Mitotic arrest deficient homolog like 2 antibody|Mitotic arrest deficient like 2 (yeast) antibody|Mitotic arrest deficient yeast homolog antibody|Mitotic spindle assembly checkpoint protein MAD2B antibody|Polymerase (DNA directed) zeta 2 accessory subunit antibody|POLZ2 antibody|REV 7 antibody|REV7 antibody|REV7 homolog antibody|Weakly similar to Mitotic MAD2 protein (S cerevisiae) antibody|Anti-Mad2L2 antibody [EPR13657] (ab180579)
SCBT cat No: sc-135977|sc-27731|sc-377367|
Rabbit polyclonal MAD2L2 antibody
|Catalogue No.|| |
Human, Mouse, Rat
Recombinant protein of human MAD2L2
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
Predicted: 24kDa/Observed: Refer to figures
MAD2L2 antibody was tube-contained.
MAD2L2 antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Database links|| |
|Protein function|| |
Adapter protein able to interact with different proteins and involved in different biological processes. Mediates the interaction between the error-prone DNA polymerase zeta catalytic subunit REV3L and the inserter polymerase REV1, thereby mediating the second polymerase switching in translesion DNA synthesis. Translesion DNA synthesis releases the replication blockade of replicative polymerases, stalled in presence of DNA lesions. May also regulate another aspect of cellular response to DNA damage through regulation of the JNK-mediated phosphorylation and activation of the transcriptional activator ELK1. Inhibits the FZR1- and probably CDC20-mediated activation of the anaphase promoting complex APC thereby regulating progression through the cell cycle. Regulates TCF7L2-mediated gene transcription and may play a role in epithelial-mesenchymal transdifferentiation.
|Protein tissue specificity|| |
|Protein sequence and domain|| |
Contains 1 HORMA domain.
|Protein cellular localization|| |
Nucleus. Cytoplasm, cytoskeleton, spindle. Cytoplasm.
AntibodyPlus can customize MAD2L2 antibody according to your requirement, including bulk product size,etc. Please contact firstname.lastname@example.org. AntibodyPlus provides antibody trial sample for your own antibody validation.
|Product type|| |
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