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Rabbit polyclonal MAFB antibody (A10077)
Supplier: ABclonal Inc.
Recommended applications: WB
WB 1:500 – 1:2000
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit polyclonal MAFB antibody.
Check alternative names for the antibodyExpand
Kreisler antibody|KRML antibody|Maf-B antibody|Mafb antibody|MAFB/Kreisler basic region/leucine zipper transcription factor antibody|MAFB_HUMAN antibody|MGC43127 antibody|Segmentation protein KR antibody|Transcription factor MafB antibody|V maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian) antibody|V-maf musculoaponeurotic fibrosarcoma oncogene homolog B antibody|Anti-MafB antibody (ab66506)
SCBT cat No: sc-7866|sc-10017|sc-365023|sc-131130|sc-100486|sc-398296|
Rabbit polyclonal MAFB antibody
|Catalogue No.|| |
Human, Mouse, Rat
Recombinant protein of human MAFB
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
Predicted: 36kDa/Observed: Refer to figures
MAFB antibody was tube-contained.
MAFB antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Database links|| |
|Protein function|| |
Acts as a transcriptional activator or repressor. Plays a pivotal role in regulating lineage-specific hematopoiesis by repressing ETS1-mediated transcription of erythroid-specific genes in myeloid cells. Required for monocytic, macrophage, osteoclast, podocyte and islet beta cell differentiation. Involved in renal tubule survival and F4/80 maturation. Activates the insulin and glucagon promoters. Together with PAX6, transactivates weakly the glucagon gene promoter through the G1 element. SUMO modification controls its transcriptional activity and ability to specify macrophage fate. Binds element G1 on the glucagon promoter (By similarity). Involved either as an oncogene or as a tumor suppressor, depending on the cell context.
|Protein tissue specificity|| |
|Protein sequence and domain|| |
The leucine-zipper domain is involved in the interaction with LRPICD.Belongs to the bZIP family. Maf subfamily.; Contains 1 bZIP (basic-leucine zipper) domain.
|Protein post-translational modifications|| |
Phosphorylated by GSK3 and MAPK13 on serine and threonine residues.; Sumoylated. Sumoylation on Lys-32 and Lys-297 stimulates its transcriptional repression activity and promotes macrophage differentiation from myeloid progenitors (By similarity).
|Protein cellular localization|| |
AntibodyPlus can customize MAFB antibody according to your requirement, including bulk product size,etc. Please contact firstname.lastname@example.org. AntibodyPlus provides antibody trial sample for your own antibody validation.
|Product type|| |
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