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Rabbit polyclonal MAGEA1 antibody (A5470)
Supplier: ABclonal Inc.
Recommended applications: WB,IHC,IF
WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:100
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit polyclonal MAGEA1 antibody.
Check alternative names for the antibodyExpand
CT1.1 antibody, MAGE1 antibody
Antigen MZ2 E antibody|Antigen MZ2-E antibody|Cancer/testis antigen 1.1 antibody|cancer/testis antigen family 1, member 1 antibody|CT1.1 antibody|MAGA1_HUMAN antibody|MAGE 1 antigen antibody|MAGE-1 antigen antibody|MAGE1 antibody|MAGE1A antibody|MAGEA1 antibody|Melanoma antigen 1 antibody|Melanoma antigen family A 1 (directs expression of antigen MZ2 E) antibody|Melanoma antigen family A 1 antibody|Melanoma antigen MAGE 1 antibody|Melanoma associated antigen 1 antibody|Melanoma associated antigen MZ2 E antibody|Melanoma-associated antigen 1 antibody|MGC9326 antibody|Anti-MAGE 1 antibody (ab21472)
SCBT cat No: sc-71536|sc-71537|sc-12805|sc-20034|sc-71539|
Rabbit polyclonal MAGEA1 antibody
|Catalogue No.|| |
Recombinant protein of human MAGEA1
WB, IHC, IF
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
Predicted: 34kDa/Observed: Refer to figures
MAGEA1 antibody was tube-contained.
MAGEA1 antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Alternative antibody names|| |
CT1.1 antibody, MAGE1 antibody
|Database links|| |
|Protein names|| |
|Protein function|| |
May be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.
|Protein tissue specificity|| |
Expressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for testes. Never expressed in kidney tumors, leukemias and lymphomas.
|Protein sequence and domain|| |
Contains 1 MAGE domain.
|Protein cellular localization|| |
This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita.
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|Product type|| |
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