Rabbit polyclonal MAGEA1 antibody (A5470)

$69.00$259.00

Reactivity: Human,Mouse
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal MAGEA1 antibody (A5470)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:100

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal MAGEA1 antibody.

Alternative names:

Check alternative names for the antibody

Expand

CT1.1 antibody, MAGE1 antibody
Antigen MZ2 E antibody|Antigen MZ2-E antibody|Cancer/testis antigen 1.1 antibody|cancer/testis antigen family 1, member 1 antibody|CT1.1 antibody|MAGA1_HUMAN antibody|MAGE 1 antigen antibody|MAGE-1 antigen antibody|MAGE1 antibody|MAGE1A antibody|MAGEA1 antibody|Melanoma antigen 1 antibody|Melanoma antigen family A 1 (directs expression of antigen MZ2 E) antibody|Melanoma antigen family A 1 antibody|Melanoma antigen MAGE 1 antibody|Melanoma associated antigen 1 antibody|Melanoma associated antigen MZ2 E antibody|Melanoma-associated antigen 1 antibody|MGC9326 antibody|Anti-MAGE 1 antibody (ab21472)

SCBT cat No: sc-71536|sc-71537|sc-12805|sc-20034|sc-71539|

Name

Rabbit polyclonal MAGEA1 antibody

Catalogue No.

A5470

Reactivity

Human, Mouse

Immunogen

Recombinant protein of human MAGEA1

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:100

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 34kDa/Observed: Refer to figures

Formulation

MAGEA1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

MAGEA1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

CT1.1 antibody, MAGE1 antibody

Database links

Human UniProt/Swiss-Prot:P43355

Protein names

CT1.1, MAGE1

Protein function

May be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.

Protein tissue specificity

Expressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for testes. Never expressed in kidney tumors, leukemias and lymphomas.

Protein sequence and domain

Contains 1 MAGE domain.

Protein cellular localization

Cytoplasm. Nucleus.

Background

This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita.

Research area

All research areas>Tumor Suppressor/Apoptosis>MAGE
(View all antibody categories related to Tumor Suppressor/Apoptosis)

Note

AntibodyPlus can customize MAGEA1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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