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Rabbit polyclonal MANF antibody (A7005)
Supplier: ABclonal Inc.
Recommended applications: WB,IHC,IF
WB 1:500 – 1:2000 IHC 1:50 – 1:100 IF 1:50 – 1:100
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit polyclonal MANF antibody.
Check alternative names for the antibodyExpand
ARP antibody, ARMET antibody
Arginine rich mutated in early stage tumors antibody|Arginine rich protein antibody|Arginine-rich protein antibody|ARMET antibody|ARMET protein antibody|ARP antibody|Manf antibody|MANF_HUMAN antibody|Mesencephalic astrocyte derived neurotrophic factor antibody|Mesencephalic astrocyte-derived neurotrophic factor antibody|MGC142148 antibody|MGC142150 antibody|Protein ARMET antibody|Anti-ARMET antibody (ab67271)
SCBT cat No: sc-517093|sc-34560|sc-34562|
Rabbit polyclonal MANF antibody
|Catalogue No.|| |
Human, Mouse, Rat
Recombinant protein of human MANF
WB, IHC, IF
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
Predicted: 21kDa/Observed: Refer to figures
MANF antibody was tube-contained.
MANF antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Alternative antibody names|| |
ARP antibody, ARMET antibody
|Database links|| |
|Protein names|| |
|Protein function|| |
Selectively promotes the survival of dopaminergic neurons of the ventral mid-brain. Modulates GABAergic transmission to the dopaminergic neurons of the substantia nigra. Enhances spontaneous, as well as evoked, GABAergic inhibitory postsynaptic currents in dopaminergic neurons (By similarity). Inhibits cell proliferation and endoplasmic reticulum (ER) stress-induced cell death.
|Protein sequence and domain|| |
The N-terminal region may be responsible for neurotrophic activity while the C-terminal region may play a role in the ER stress response.Belongs to the ARMET family.
|Protein post-translational modifications|| |
May contain sialic acid residues.
|Protein cellular localization|| |
The protein encoded by this gene is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and results in cell proliferation. Activity of this protein is important in promoting the survival of dopaminergic neurons. The presence of polymorphisms in the N-terminal arginine-rich region, including a specific mutation that changes an ATG start codon to AGG, have been reported in a variety of solid tumors; however, these polymorphisms were later shown to exist in normal tissues and are thus no longer thought to be tumor-related.
AntibodyPlus can customize MANF antibody according to your requirement, including bulk product size,etc. Please contact firstname.lastname@example.org. AntibodyPlus provides antibody trial sample for your own antibody validation.
|Product type|| |
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