Rabbit polyclonal MCAM antibody (A1962)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

Clear
-$50 as credit for submitting review for primary antibody
Shipping notice:
Product will be delivered in 6 to 8 Business Days

Rabbit polyclonal MCAM antibody (A1962)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:1000 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal MCAM antibody.

Alternative names:

Check alternative names for the antibody

Expand

CD146 antibody, MUC18 antibody
A32 antigen antibody|CD 146 antibody|CD146 antibody|CD146 antigen antibody|Cell surface glycoprotein MUC18 antibody|Cell surface glycoprotein P1H12 antibody|Gicerin antibody|Mcam antibody|Melanoma adhesion molecule antibody|Melanoma associated antigen A32 antibody|Melanoma associated antigen MUC18 antibody|Melanoma associated glycoprotein MUC18 antibody|Melanoma cell adhesion molecule antibody|Melanoma-associated antigen A32 antibody|Melanoma-associated antigen MUC18 antibody|MelCAM antibody|MUC 18 antibody|MUC18 antibody|MUC18_HUMAN antibody|S endo 1 antibody|S endo 1 endothelial associated antigen antibody|S-endo 1 endothelial-associated antigen antibody|Anti-CD146 antibody [EPR3208] (ab75769)

SCBT cat No: sc-135987|sc-71565|sc-71564|sc-374556|sc-376762|sc-374414|sc-18942|sc-28667|sc-18940|sc-53369|sc-18837|

Name

Rabbit polyclonal MCAM antibody

Catalogue No.

A1962

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human MCAM

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:1000 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 72kDa/Observed: Refer to figures

Formulation

MCAM antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

MCAM antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

CD146 antibody, MUC18 antibody

Database links

Human UniProt/Swiss-Prot:P43121

Protein names

CD146, MUC18

Protein function

Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.

Protein tissue specificity

Detected in endothelial cells in vascular tissue throughout the body. May appear at the surface of neural crest cells during their embryonic migration. Appears to be limited to vascular smooth muscle in normal adult tissues. Associated with tumor progression and the development of metastasis in human malignant melanoma. Expressed most strongly on metastatic lesions and advanced primary tumors and is only rarely detected in benign melanocytic nevi and thin primary melanomas with a low probability of metastasis.

Protein sequence and domain

Contains 3 Ig-like C2-type (immunoglobulin-like) domains.; Contains 2 Ig-like V-type (immunoglobulin-like) domains.

Protein cellular localization

Membrane; Single-pass type I membrane protein.

Note

AntibodyPlus can customize MCAM antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

Reviews


There are no reviews yet.

Only logged in customers who have purchased this product may leave a review

There are no reviews for this product yet.
By submitting a review, get following benefits:

1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!

view database submit reviews

There is no extra validation for this product yet.
Check other extra validated antibodies below:



Welcome to AntibodyPlus!