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Rabbit polyclonal MCAM antibody (A1962)
Supplier: ABclonal Inc.
Recommended applications: WB,IHC
WB 1:1000 – 1:2000 IHC 1:50 – 1:200
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit polyclonal MCAM antibody.
Check alternative names for the antibodyExpand
CD146 antibody, MUC18 antibody
A32 antigen antibody|CD 146 antibody|CD146 antibody|CD146 antigen antibody|Cell surface glycoprotein MUC18 antibody|Cell surface glycoprotein P1H12 antibody|Gicerin antibody|Mcam antibody|Melanoma adhesion molecule antibody|Melanoma associated antigen A32 antibody|Melanoma associated antigen MUC18 antibody|Melanoma associated glycoprotein MUC18 antibody|Melanoma cell adhesion molecule antibody|Melanoma-associated antigen A32 antibody|Melanoma-associated antigen MUC18 antibody|MelCAM antibody|MUC 18 antibody|MUC18 antibody|MUC18_HUMAN antibody|S endo 1 antibody|S endo 1 endothelial associated antigen antibody|S-endo 1 endothelial-associated antigen antibody|Anti-CD146 antibody [EPR3208] (ab75769)
SCBT cat No: sc-135987|sc-71565|sc-71564|sc-374556|sc-376762|sc-374414|sc-18942|sc-28667|sc-18940|sc-53369|sc-18837|
Rabbit polyclonal MCAM antibody
|Catalogue No.|| |
Human, Mouse, Rat
Recombinant protein of human MCAM
|Recommended dilution|| |
WB 1:1000 – 1:2000
|Molecular weight|| |
Predicted: 72kDa/Observed: Refer to figures
MCAM antibody was tube-contained.
MCAM antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Alternative antibody names|| |
CD146 antibody, MUC18 antibody
|Database links|| |
|Protein names|| |
|Protein function|| |
Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.
|Protein tissue specificity|| |
Detected in endothelial cells in vascular tissue throughout the body. May appear at the surface of neural crest cells during their embryonic migration. Appears to be limited to vascular smooth muscle in normal adult tissues. Associated with tumor progression and the development of metastasis in human malignant melanoma. Expressed most strongly on metastatic lesions and advanced primary tumors and is only rarely detected in benign melanocytic nevi and thin primary melanomas with a low probability of metastasis.
|Protein sequence and domain|| |
Contains 3 Ig-like C2-type (immunoglobulin-like) domains.; Contains 2 Ig-like V-type (immunoglobulin-like) domains.
|Protein cellular localization|| |
Membrane; Single-pass type I membrane protein.
AntibodyPlus can customize MCAM antibody according to your requirement, including bulk product size,etc. Please contact email@example.com. AntibodyPlus provides antibody trial sample for your own antibody validation.
|Product type|| |
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