Rabbit polyclonal MFN1 antibody (A9880)


Reactivity: Human,Mouse,Rat
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal MFN1 antibody (A9880)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:500 – 1:2000

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal MFN1 antibody.

Alternative names:

Check alternative names for the antibody


Fzo homolog antibody|Hfzo1 antibody|Hfzo2 antibody|MFN 1 antibody|Mfn1 antibody|MFN1_HUMAN antibody|Mitochondrial transmembrane GTPase Fzo 1 antibody|Mitochondrial transmembrane GTPase FZO 2 antibody|Mitochondrial transmembrane GTPase FZO1B antibody|Mitofusin 1 antibody|Mitofusin-1 antibody|Mitofusin1 antibody|MS996 antibody|Putative transmembrane GTPase antibody|Transmembrane GTPase MFN1 antibody|Anti-Mitofusin 1 antibody (ab57602)

SCBT cat No: sc-166644|sc-50330|sc-30363|


Rabbit polyclonal MFN1 antibody

Catalogue No.



Human, Mouse, Rat


Recombinant protein of human MFN1





Recommended dilution

WB 1:500 – 1:2000







Molecular weight

Predicted: 84kDa/Observed: Refer to figures


MFN1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.


MFN1 antibody was purified using affinity purification.


Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Database links

Human UniProt/Swiss-Prot:Q8IWA4

Protein function

Essential transmembrane GTPase, which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. MFN1 acts independently of the cytoskeleton. Overexpression induces the formation of mitochondrial networks.

Protein tissue specificity

Ubiquitous. Expressed at slightly higher level in kidney and heart. Isoform 2 may be overexpressed in some tumors, such as lung cancers.

Protein sequence and domain

Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. Mitofusin subfamily.; Contains 1 dynamin-type G (guanine nucleotide-binding) domain.

Protein post-translational modifications

Ubiquitinated by non-degradative ubiquitin by PARK2, promoting mitochondrial fusion; deubiquitination by USP30 inhibits mitochondrial fusion (By similarity). Ubiquitinated by MARCH5. When mitochondria are depolarized and dysfunctional, it is ubiquitinated by a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex that contains FBXO7 and PARK2.

Protein cellular localization

Mitochondrion outer membrane ; Multi-pass membrane protein .; Isoform 2: Cytoplasm.

Research area

All research areas>Synthesis and Degradation>Mfn
(View all antibody categories related to Synthesis and Degradation)


AntibodyPlus can customize MFN1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody


ABclonal Inc.


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