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Rabbit polyclonal MLF1 antibody (A8012)
Supplier: ABclonal Inc.
Recommended applications: WB,IF
WB 1:500 – 1:2000 IF 1:50 – 1:100
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit polyclonal MLF1 antibody.
Check alternative names for the antibodyExpand
Hls7 antibody|MLF1 antibody|MLF1_HUMAN antibody|Myelodysplasia myeloid leukemia factor 1 antibody|Myelodysplasia-myeloid leukemia factor 1 antibody|Myeloid leukemia factor 1 antibody|myeloid leukemia factor 1 variant 1 antibody|myeloid leukemia factor 1 variant 2 antibody|myeloid leukemia factor 1 variant 3 antibody|Anti-Myeloid leukemia factor 1 antibody (ab103099)
SCBT cat No: sc-514304|sc-514294|sc-134895|
Rabbit polyclonal MLF1 antibody
|Catalogue No.|| |
Recombinant protein of human MLF1
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
Predicted: 31kDa/Observed: Refer to figures
MLF1 antibody was tube-contained.
MLF1 antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Database links|| |
|Protein function|| |
Involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. Interferes with erythropoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. Suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. Binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.
|Protein tissue specificity|| |
Most abundant in testis, ovary, skeletal muscle, heart, kidney and colon. Low expression in spleen, thymus and peripheral blood leukocytes.
|Protein sequence and domain|| |
Belongs to the MLF family.
|Protein post-translational modifications|| |
Phosphorylation is required for binding to YWHAZ.
|Protein cellular localization|| |
Cytoplasm . Nucleus . Note: Shuttles between the cytoplasm and nucleus.
This gene encodes an oncoprotein which is thought to play a role in the phenotypic determination of hemopoetic cells. Translocations between this gene and nucleophosmin have been associated with myelodysplastic syndrome and acute myeloid leukemia. Multiple transcript variants encoding different isoforms have been found for this gene.
AntibodyPlus can customize MLF1 antibody according to your requirement, including bulk product size,etc. Please contact email@example.com. AntibodyPlus provides antibody trial sample for your own antibody validation.
|Product type|| |
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