Rabbit polyclonal MME antibody (A5664)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IP,FC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

Clear
-$50 as credit for submitting review for primary antibody
Shipping notice:
Product will be delivered in 6 to 8 Business Days

Rabbit polyclonal MME antibody (A5664)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IP,FC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IP 1:20 – 1:50 FC 1:20 – 1:50

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal MME antibody.

Alternative names:

Check alternative names for the antibody

Expand

NEP antibody, SFE antibody, CD10 antibody, CALLA antibody
Atriopeptidase antibody|CALLA antibody|CD10 antibody|CD10 antigen antibody|Common acute lymphocytic leukemia antigen antibody|DKFZp686O16152 antibody|EC 3.4.24.11 antibody|Enkephalinase antibody|EPN antibody|Membrane metallo endopeptidase (neutral endopeptidase, enkephalinase) antibody|Membrane metallo endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10) antibody|Membrane metallo endopeptidase antibody|Membrane metallo endopeptidase variant 1 antibody|Membrane metallo endopeptidase variant 2 antibody|Membrane metalloendopeptidase antibody|Membrane metalloendopeptidase neutral endopeptidase enkephalinase antibody|Membrane metalloendopeptidase neutral endopeptidase enkephalinase CALLA CD10 antibody|Membrane metalloendopeptidase variant 1 antibody|Membrane metalloendopeptidase variant 2 antibody|MGC126681 antibody|MGC126707 antibody|MME antibody|NEP antibody|NEP_HUMAN antibody|Neprilysin antibody|neprilysin-390 antibody|neprilysin-411 antibody|Neutral endopeptidase 24.11 antibody|Neutral endopeptidase antibody|Neutral endopeptidase, membrane-associated antibody|SFE antibody|Skin fibroblast elastase antibody|Anti-CD10 antibody [56C6] (ab951)

SCBT cat No: sc-65990|sc-19993|sc-52455|sc-102424|sc-46656|sc-7632|sc-9149|sc-102426|sc-80544|

Name

Rabbit polyclonal MME antibody

Catalogue No.

A5664

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human MME

Host

Rabbit

Applications

WB, IHC, IP, FC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IP 1:20 – 1:50
FC 1:20 – 1:50

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 85kDa/Observed: Refer to Figures

Formulation

MME antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

MME antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

NEP antibody, SFE antibody, CD10 antibody, CALLA antibody

Database links

Human UniProt/Swiss-Prot:P08473

Protein names

NEP, SFE, CD10, CALLA

Protein function

Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids . Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond . Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9 . Involved in the degradation of atrial natriuretic factor (ANF) . Displays UV-inducible elastase activity toward skin preelastic and elastic fibers .

Protein sequence and domain

Belongs to the peptidase M13 family.

Protein post-translational modifications

Myristoylation is a determinant of membrane targeting.; Glycosylation at Asn-628 is necessary both for surface expression and neutral endopeptidase activity.

Protein cellular localization

Cell membrane; Single-pass type II membrane protein.

Background

This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb. The 5′ untranslated region of this gene is alternatively spliced, resulting in four separate mRNA transcripts. The coding region is not affected by alternative splicing.

Research area

All research areas>Lymphocyte Signaling>CD10 and Neprilysin
(View all antibody categories related to Lymphocyte Signaling)

Note

AntibodyPlus can customize MME antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

Reviews


There are no reviews yet.

Only logged in customers who have purchased this product may leave a review

There are no reviews for this product yet.
By submitting a review, get following benefits:

1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!

view database submit reviews

There is no extra validation for this product yet.
Check other extra validated antibodies below:



Welcome to AntibodyPlus!