Rabbit polyclonal MME antibody (A5664)


Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IP,FC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal MME antibody (A5664)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IP,FC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IP 1:20 – 1:50 FC 1:20 – 1:50

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody


NEP antibody, SFE antibody, CD10 antibody, CALLA antibody
Atriopeptidase antibody|CALLA antibody|CD10 antibody|CD10 antigen antibody|Common acute lymphocytic leukemia antigen antibody|DKFZp686O16152 antibody|EC antibody|Enkephalinase antibody|EPN antibody|Membrane metallo endopeptidase (neutral endopeptidase, enkephalinase) antibody|Membrane metallo endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10) antibody|Membrane metallo endopeptidase antibody|Membrane metallo endopeptidase variant 1 antibody|Membrane metallo endopeptidase variant 2 antibody|Membrane metalloendopeptidase antibody|Membrane metalloendopeptidase neutral endopeptidase enkephalinase antibody|Membrane metalloendopeptidase neutral endopeptidase enkephalinase CALLA CD10 antibody|Membrane metalloendopeptidase variant 1 antibody|Membrane metalloendopeptidase variant 2 antibody|MGC126681 antibody|MGC126707 antibody|MME antibody|NEP antibody|NEP_HUMAN antibody|Neprilysin antibody|neprilysin-390 antibody|neprilysin-411 antibody|Neutral endopeptidase 24.11 antibody|Neutral endopeptidase antibody|Neutral endopeptidase, membrane-associated antibody|SFE antibody|Skin fibroblast elastase antibody|Anti-CD10 antibody [56C6] (ab951)

SCBT cat No: sc-65990|sc-19993|sc-52455|sc-102424|sc-46656|sc-7632|sc-9149|sc-102426|sc-80544|


Rabbit polyclonal MME antibody

Catalogue No.



Human, Mouse, Rat


Recombinant protein of human MME





Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IP 1:20 – 1:50
FC 1:20 – 1:50







Molecular weight

Predicted: 85kDa/Observed: Refer to Figures


MME antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.


MME antibody was purified using affinity purification.


Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

NEP antibody, SFE antibody, CD10 antibody, CALLA antibody

Database links

Human UniProt/Swiss-Prot:P08473

Protein names


Protein function

Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids . Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond . Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9 . Involved in the degradation of atrial natriuretic factor (ANF) . Displays UV-inducible elastase activity toward skin preelastic and elastic fibers .

Protein sequence and domain

Belongs to the peptidase M13 family.

Protein post-translational modifications

Myristoylation is a determinant of membrane targeting.; Glycosylation at Asn-628 is necessary both for surface expression and neutral endopeptidase activity.

Protein cellular localization

Cell membrane; Single-pass type II membrane protein.


This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb. The 5′ untranslated region of this gene is alternatively spliced, resulting in four separate mRNA transcripts. The coding region is not affected by alternative splicing.

Research area

All research areas>Lymphocyte Signaling>CD10 and Neprilysin
(View all antibody categories related to Lymphocyte Signaling)


AntibodyPlus can customize MME antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody


ABclonal Inc.


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