Rabbit polyclonal MMP11 antibody (A3034)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal MMP11 antibody (A3034)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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ST3 antibody, SL-3 antibody, STMY3 antibody
Matrix Metalloproteinase 11 antibody|Matrix metalloproteinase-11 antibody|MMP-11 antibody|Mmp11 antibody|MMP11_HUMAN antibody|SL 3 antibody|SL-3 antibody|SL3 antibody|ST3 antibody|STMY3 antibody|Stromelysin 3 antibody|Stromelysin III antibody|Stromelysin-3 antibody|Anti-MMP11 antibody [EP1259Y] (ab52904)

SCBT cat No: sc-8836|sc-8837|sc-58381|

Name

Rabbit polyclonal MMP11 antibody

Catalogue No.

A3034

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide of human MMP11

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 55kDa/Observed: Refer to Figures

Formulation

MMP11 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

MMP11 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

ST3 antibody, SL-3 antibody, STMY3 antibody

Database links

Human UniProt/Swiss-Prot:P24347

Protein names

ST3, SL-3, STMY3

Protein function

May play an important role in the progression of epithelial malignancies.

Protein tissue specificity

Specifically expressed in stromal cells of breast carcinomas.

Protein sequence and domain

The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.Belongs to the peptidase M10A family.; Contains 4 hemopexin repeats.

Protein post-translational modifications

The precursor is cleaved by a furin endopeptidase.

Protein cellular localization

Secreted, extracellular space, extracellular matrix .

Background

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP’s are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP’s, this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix.

Research area

All research areas>Synthesis and Degradation>MMP
(View all antibody categories related to Synthesis and Degradation)

Note

AntibodyPlus can customize MMP11 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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