Rabbit polyclonal MMP7 antibody (A0695)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal MMP7 antibody (A0695)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

Expand

MMP7 antibody,MMP-7 antibody,MPSL1 antibody,PUMP-1 antibody
Matrilysin antibody|Matrin antibody|Matrix Metalloproteinase 7 antibody|Matrix metalloproteinase-7 antibody|MMP 7 antibody|MMP-7 antibody|MMP7 antibody|MMP7_HUMAN antibody|MPSL1 antibody|PUMP 1 antibody|Pump 1 protease antibody|Pump-1 protease antibody|PUMP1 antibody|Uterine matrilysin antibody|Uterine metalloproteinase antibody|Anti-MMP7 antibody (ab5706)

SCBT cat No: sc-26680|sc-30071|

Name

Rabbit polyclonal MMP7 antibody

Catalogue No.

A0695

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human MMP7

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 29kDa/Observed: Refer to Figures

Formulation

MMP7 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

MMP7 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

MMP7 antibody,MMP-7 antibody,MPSL1 antibody,PUMP-1 antibody

Database links

Human UniProt/Swiss-Prot:P09237

Protein names

MMP7,MMP-7,MPSL1,PUMP-1

Protein function

Degrades casein, gelatins of types I, III, IV, and V, and fibronectin. Activates procollagenase.

Protein sequence and domain

The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.Belongs to the peptidase M10A family.

Protein cellular localization

Secreted, extracellular space, extracellular matrix .

Background

The matrix metalloproteinases (MMPs) are a family of proteases that target many extracellular proteins including other proteases, growth factors, cell surface receptors and adhesion molecules (1). Among the family members, MMP-2, MMP-3, MMP-7 and MMP-9 have been characterized as important factors for normal tissue remodeling during embryonic development, wound healing, tumor invasion, angiogenesis, carcinogenesis and apoptosis (2-4). MMP activity correlates with cancer development (2). One mechanism of MMP regulation is transcriptional (5). Once synthesized, MMP exists as a latent proenzyme. Maximum MMP activity requires proteolytic cleavage to generate active MMPs by releasing the inhibitory propeptide domain from the full length protein (5).

Research area

All research areas>Synthesis and Degradation>MMP
(View all antibody categories related to Synthesis and Degradation)

Note

AntibodyPlus can customize MMP7 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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