Rabbit polyclonal MNAT1 antibody (A1918)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal MNAT1 antibody (A1918)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal MNAT1 antibody.

Alternative names:

Check alternative names for the antibody

Expand

MAT1 antibody, TFB3 antibody, CAP35 antibody, RNF66 antibody
MNAT 1 antibody|CAP35 antibody|CDK activating kinase assembly factor MAT1 antibody|CDK-activating kinase assembly factor MAT1 antibody|CDK7/cyclin H assembly factor antibody|CDK7/cyclin-H assembly factor antibody|Cyclin G1 interacting protein antibody|Cyclin-G1-interacting protein antibody|MAT1 antibody|MAT1_HUMAN antibody|Menage a trois 1 (CAK assembly factor) antibody|Menage a trois antibody|Menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis) antibody|MNAT CDK activating kinase assembly factor 1 antibody|Mnat1 antibody|p35 antibody|p36 antibody|RING finger protein 66 antibody|RING finger protein MAT1 antibody|RNF66 antibody|TFB3 antibody|Anti-MNAT1 antibody [EPR10940] (ab169546)

SCBT cat No: sc-136540|sc-135981|sc-13142|sc-6234|sc-1600|

Name

Rabbit polyclonal MNAT1 antibody

Catalogue No.

A1918

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human MNAT1

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 36kDa/Observed: Refer to Figures

Formulation

MNAT1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

MNAT1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

MAT1 antibody, TFB3 antibody, CAP35 antibody, RNF66 antibody

Database links

Human UniProt/Swiss-Prot:P51948

Protein names

MAT1, TFB3, CAP35, RNF66

Protein function

Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II.

Protein tissue specificity

Highest levels in colon and testis. Moderate levels are present thymus, prostate, ovary, and small intestine. The lowest levels are found in spleen and leukocytes.

Protein sequence and domain

Contains 1 RING-type zinc finger.; Contains 1 UIM (ubiquitin-interacting motif) domain.

Protein cellular localization

Nucleus.

Background

The protein encoded by this gene, along with cyclin H and CDK7, forms the CDK-activating kinase (CAK) enzymatic complex. This complex activates several cyclin-associated kinases and can also associate with TFIIH to activate transcription by RNA polymerase II. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

Research area

All research areas>Cell Cycle Proteins>Mat1
(View all antibody categories related to Cell Cycle Proteins)

Note

AntibodyPlus can customize MNAT1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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