Rabbit polyclonal MOCS3 antibody (A7367)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal MOCS3 antibody (A7367)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal MOCS3 antibody.

Alternative names:

Check alternative names for the antibody

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UBA4 antibody
Adenylyltransferase MOCS3 antibody|dJ914P20.3 antibody|MGC9252 antibody|MOCS 3 antibody|MOCS3 antibody|MOCS3_HUMAN antibody|Molybdenum cofactor synthesis 3 antibody|Molybdenum cofactor synthesis protein 3 antibody|Molybdopterin synthase sulfurylase antibody|Molybdopterin-synthase sulfurtransferase antibody|MPT synthase sulfurylase antibody|Sulfur carrier protein MOCS2A adenylyltransferase antibody|Sulfur carrier protein MOCS2A sulfurtransferase antibody|Sulfurtransferase MOCS3 antibody|UBA 4 antibody|UBA4 ubiquitin activating enzyme E1 homolog antibody|UBA4 antibody|Anti-MOCS3 antibody – N-terminal (ab139062)

SCBT cat No: sc-100562|

Name

Rabbit polyclonal MOCS3 antibody

Catalogue No.

A7367

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human MOCS3

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 50kDa/Observed: Refer to figures

Formulation

MOCS3 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

MOCS3 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

UBA4 antibody

Database links

Human UniProt/Swiss-Prot:O95396

Protein names

UBA4

Protein function

Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (-COSH) of their C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1 and MOCS2A. Subsequently, a transient disulfide bond is formed. Does not use thiosulfate as sulfur donor; NFS1 probably acting as a sulfur donor for thiocarboxylation reactions.

Protein sequence and domain

In the N-terminal section; belongs to the HesA/MoeB/ThiF family. UBA4 subfamily.; Contains 1 rhodanese domain.

Protein cellular localization

Cytoplasm .

Background

Molybdenum cofactor (MoCo) is necessary for the function of all molybdoenzymes. The protein encoded by this gene adenylates and activates molybdopterin synthase, an enzyme required for biosynthesis of MoCo. This gene contains no introns. A pseudogene of this gene is present on chromosome 14.

Note

AntibodyPlus can customize MOCS3 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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