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Rabbit polyclonal MOCS3 antibody (A7367)
Supplier: ABclonal Inc.
Recommended applications: WB,IHC,IF
WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit polyclonal MOCS3 antibody.
Check alternative names for the antibodyExpand
Adenylyltransferase MOCS3 antibody|dJ914P20.3 antibody|MGC9252 antibody|MOCS 3 antibody|MOCS3 antibody|MOCS3_HUMAN antibody|Molybdenum cofactor synthesis 3 antibody|Molybdenum cofactor synthesis protein 3 antibody|Molybdopterin synthase sulfurylase antibody|Molybdopterin-synthase sulfurtransferase antibody|MPT synthase sulfurylase antibody|Sulfur carrier protein MOCS2A adenylyltransferase antibody|Sulfur carrier protein MOCS2A sulfurtransferase antibody|Sulfurtransferase MOCS3 antibody|UBA 4 antibody|UBA4 ubiquitin activating enzyme E1 homolog antibody|UBA4 antibody|Anti-MOCS3 antibody – N-terminal (ab139062)
SCBT cat No: sc-100562|
Rabbit polyclonal MOCS3 antibody
|Catalogue No.|| |
Human, Mouse, Rat
Recombinant protein of human MOCS3
WB, IHC, IF
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
Predicted: 50kDa/Observed: Refer to figures
MOCS3 antibody was tube-contained.
MOCS3 antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Alternative antibody names|| |
|Database links|| |
|Protein names|| |
|Protein function|| |
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (-COSH) of their C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1 and MOCS2A. Subsequently, a transient disulfide bond is formed. Does not use thiosulfate as sulfur donor; NFS1 probably acting as a sulfur donor for thiocarboxylation reactions.
|Protein sequence and domain|| |
In the N-terminal section; belongs to the HesA/MoeB/ThiF family. UBA4 subfamily.; Contains 1 rhodanese domain.
|Protein cellular localization|| |
Molybdenum cofactor (MoCo) is necessary for the function of all molybdoenzymes. The protein encoded by this gene adenylates and activates molybdopterin synthase, an enzyme required for biosynthesis of MoCo. This gene contains no introns. A pseudogene of this gene is present on chromosome 14.
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|Product type|| |
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