Rabbit polyclonal MRC2 antibody (A9858)

$69.00$259.00

Reactivity: Human,Mouse
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal MRC2 antibody (A9858)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:200 – 1:500

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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C-type lectin domain family 13 member E antibody|C-type mannose receptor 2 antibody|CD 280 antibody|CD280 antibody|CD280 antigen antibody|CLEC 13E antibody|CLEC13E antibody|ENDO 180 antibody|ENDO180 antibody|Endocytic receptor (macrophage mannose receptor family) antibody|Endocytic receptor 180 antibody|FLJ35911 antibody|KIAA0709 antibody|Macrophage mannose receptor 2 antibody|Mannose receptor C type 2 antibody|MRC 2 antibody|MRC2 antibody|MRC2_HUMAN antibody|UPAR-associated protein antibody|UPARAP antibody|Urokinase plasminogen activator receptor associated protein antibody|Urokinase receptor associated protein antibody|Urokinase receptor-associated protein antibody|Urokinase-type plasminogen activator receptor-associated protein antibody|Anti-MRC2 antibody (ab70132)

SCBT cat No: sc-271148|sc-68371|

Name

Rabbit polyclonal MRC2 antibody

Catalogue No.

A9858

Reactivity

Human, Mouse

Immunogen

Recombinant protein of human MRC2

Host

Rabbit

Applications

WB

Recommended dilution

WB 1:200 – 1:500

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 167kDa/Observed: Refer to figures

Formulation

MRC2 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

MRC2 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Database links

Human UniProt/Swiss-Prot:Q9UBG0

Protein function

May play a role as endocytotic lectin receptor displaying calcium-dependent lectin activity. Internalizes glycosylated ligands from the extracellular space for release in an endosomal compartment via clathrin-mediated endocytosis. May be involved in plasminogen activation system controlling the extracellular level of PLAUR/PLAU, and thus may regulate protease activity at the cell surface. May contribute to cellular uptake, remodeling and degradation of extracellular collagen matrices. May play a role during cancer progression as well as in other chronic tissue destructive diseases acting on collagen turnover. May participate in remodeling of extracellular matrix cooperating with the matrix metalloproteinases (MMPs).

Protein tissue specificity

Ubiquitous with low expression in brain, placenta, lung, kidney, pancreas, spleen, thymus and colon. Expressed in endothelial cells, fibroblasts and macrophages. Highly expressed in fetal lung and kidney.

Protein sequence and domain

C-type lectin domains 3 to 8 are not required for calcium-dependent binding of mannose, fucose and N-acetylglucosamine. C-type lectin domain 2 is responsible for sugar-binding in a calcium-dependent manner.; Fibronectin type-II domain mediates collagen-binding.; Ricin B-type lectin domain contacts with the second C-type lectin domain.Contains 8 C-type lectin domains.; Contains 1 fibronectin type-II domain.; Contains 1 ricin B-type lectin domain.

Protein post-translational modifications

N-glycosylated.

Protein cellular localization

Membrane; Single-pass type I membrane protein.

Research area

All research areas>Lymphocyte Signaling>Endo180
(View all antibody categories related to Lymphocyte Signaling)

Note

AntibodyPlus can customize MRC2 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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