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Rabbit polyclonal MRC2 antibody (A9858)
Supplier: ABclonal Inc.
Recommended applications: WB
WB 1:200 – 1:500
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit polyclonal MRC2 antibody.
Check alternative names for the antibodyExpand
C-type lectin domain family 13 member E antibody|C-type mannose receptor 2 antibody|CD 280 antibody|CD280 antibody|CD280 antigen antibody|CLEC 13E antibody|CLEC13E antibody|ENDO 180 antibody|ENDO180 antibody|Endocytic receptor (macrophage mannose receptor family) antibody|Endocytic receptor 180 antibody|FLJ35911 antibody|KIAA0709 antibody|Macrophage mannose receptor 2 antibody|Mannose receptor C type 2 antibody|MRC 2 antibody|MRC2 antibody|MRC2_HUMAN antibody|UPAR-associated protein antibody|UPARAP antibody|Urokinase plasminogen activator receptor associated protein antibody|Urokinase receptor associated protein antibody|Urokinase receptor-associated protein antibody|Urokinase-type plasminogen activator receptor-associated protein antibody|Anti-MRC2 antibody (ab70132)
SCBT cat No: sc-271148|sc-68371|
Rabbit polyclonal MRC2 antibody
|Catalogue No.|| |
Recombinant protein of human MRC2
|Recommended dilution|| |
WB 1:200 – 1:500
|Molecular weight|| |
Predicted: 167kDa/Observed: Refer to figures
MRC2 antibody was tube-contained.
MRC2 antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Database links|| |
|Protein function|| |
May play a role as endocytotic lectin receptor displaying calcium-dependent lectin activity. Internalizes glycosylated ligands from the extracellular space for release in an endosomal compartment via clathrin-mediated endocytosis. May be involved in plasminogen activation system controlling the extracellular level of PLAUR/PLAU, and thus may regulate protease activity at the cell surface. May contribute to cellular uptake, remodeling and degradation of extracellular collagen matrices. May play a role during cancer progression as well as in other chronic tissue destructive diseases acting on collagen turnover. May participate in remodeling of extracellular matrix cooperating with the matrix metalloproteinases (MMPs).
|Protein tissue specificity|| |
Ubiquitous with low expression in brain, placenta, lung, kidney, pancreas, spleen, thymus and colon. Expressed in endothelial cells, fibroblasts and macrophages. Highly expressed in fetal lung and kidney.
|Protein sequence and domain|| |
C-type lectin domains 3 to 8 are not required for calcium-dependent binding of mannose, fucose and N-acetylglucosamine. C-type lectin domain 2 is responsible for sugar-binding in a calcium-dependent manner.; Fibronectin type-II domain mediates collagen-binding.; Ricin B-type lectin domain contacts with the second C-type lectin domain.Contains 8 C-type lectin domains.; Contains 1 fibronectin type-II domain.; Contains 1 ricin B-type lectin domain.
|Protein post-translational modifications|| |
|Protein cellular localization|| |
Membrane; Single-pass type I membrane protein.
AntibodyPlus can customize MRC2 antibody according to your requirement, including bulk product size,etc. Please contact firstname.lastname@example.org. AntibodyPlus provides antibody trial sample for your own antibody validation.
|Product type|| |
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