Rabbit polyclonal MSR1 antibody (A1923)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

Clear
-$50 as credit for submitting review for primary antibody
Shipping notice:
Product will be delivered in 6 to 8 Business Days

Rabbit polyclonal MSR1 antibody (A1923)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:10 – 1:100

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal MSR1 antibody.

Alternative names:

Check alternative names for the antibody

Expand

SRA antibody, SR-A antibody, CD204 antibody, phSR1 antibody, phSR2 antibody, SCARA1 antibody
CD204 antibody|CD204 antigen antibody|CD24 antibody|Macrophage acetylated LDL receptor I and II antibody|Macrophage scavenger receptor 1 antibody|Macrophage scavenger receptor type III antibody|Macrophage scavenger receptor types I and II antibody|Msr 1 antibody|MSR1 antibody|MSRE_HUMAN antibody|phSR1 antibody|phSR2 antibody|SCARA 1 antibody|SCARA1 antibody|Scavenger receptor class A member 1 antibody|Scavenger receptor type A antibody|Scvr antibody|SR A antibody|SRA antibody|Anti-Macrophage Scavenger Receptor I antibody (ab123946)

SCBT cat No:

Name

Rabbit polyclonal MSR1 antibody

Catalogue No.

A1923

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human MSR1

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:10 – 1:100

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 50kDa/Observed: Refer to Figures

Formulation

MSR1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

MSR1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

SRA antibody, SR-A antibody, CD204 antibody, phSR1 antibody, phSR2 antibody, SCARA1 antibody

Database links

Human UniProt/Swiss-Prot:P21757

Protein names

SRA, SR-A, CD204, phSR1, phSR2, SCARA1

Protein function

Membrane glycoproteins implicated in the pathologic deposition of cholesterol in arterial walls during atherogenesis. Two types of receptor subunits exist. These receptors mediate the endocytosis of a diverse group of macromolecules, including modified low density lipoproteins (LDL). Isoform III does not internalize acetylated LDL.

Protein tissue specificity

Isoform I, isoform II and isoform III are expressed in monocyte-derived macrophages.

Protein sequence and domain

Contains 1 collagen-like domain.; Contains 1 SRCR domain.

Protein cellular localization

Membrane; Single-pass type II membrane protein.

Background

This gene encodes the class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing of this gene. These receptors or isoforms are macrophage-specific trimeric integral membrane glycoproteins and have been implicated in many macrophage-associated physiological and pathological processes including atherosclerosis, Alzheimer’s disease, and host defense. The isoforms type 1 and type 2 are functional receptors and are able to mediate the endocytosis of modified low density lipoproteins (LDLs). The isoform type 3 does not internalize modified LDL (acetyl-LDL) despite having the domain shown to mediate this function in the types 1 and 2 isoforms. It has an altered intracellular processing and is trapped within the endoplasmic reticulum, making it unable to perform endocytosis. The isoform type 3 can inhibit the function of isoforms type 1 and type 2 when co-expressed, indicating a dominant negative effect and suggesting a mechanism for regulation of scavenger receptor activity in macrophages. [provided by RefSeq, Jul 2008]

Note

AntibodyPlus can customize MSR1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

Reviews


There are no reviews yet.

Only logged in customers who have purchased this product may leave a review

There are no reviews for this product yet.
By submitting a review, get following benefits:

1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!

view database submit reviews

There is no extra validation for this product yet.
Check other extra validated antibodies below:



Welcome to AntibodyPlus!