Rabbit polyclonal MSRB1 antibody (A6737)

$69.00$259.00

Reactivity: Human
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal MSRB1 antibody (A6737)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:100

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal MSRB1 antibody.

Alternative names:

Check alternative names for the antibody

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SELR antibody, SELX antibody, SepR antibody, SEPX1 antibody, HSPC270 antibody
Annexin A2 like antibody|EC 1 8 4 antibody|HSPC 270 antibody|HSPC270 antibody|Methionine R sulfoxide reductase antibody|Methionine R sulfoxide reductase B1 antibody|Methionine sulfoxide reductase antibody|Methionine-R-sulfoxide reductase B1 antibody|MGC3344 antibody|MSRB 1 antibody|MsrB1 antibody|MSRB1_HUMAN antibody|OTTHUMP00000159418 antibody|Sel X antibody|Selenoprotein R antibody|Selenoprotein X 1 antibody|Selenoprotein X antibody|Selenoprotein X1 antibody|SELR antibody|SelX antibody|SEPX 1 antibody|sepx1 antibody|Anti-Methionine Sulfoxide Reductase B antibody (ab66061)

SCBT cat No:

Name

Rabbit polyclonal MSRB1 antibody

Catalogue No.

A6737

Reactivity

Human

Immunogen

Recombinant protein of human MSRB1

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:100

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 12kDa/Observed: Refer to Figures

Formulation

MSRB1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

MSRB1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

SELR antibody, SELX antibody, SepR antibody, SEPX1 antibody, HSPC270 antibody

Database links

Human UniProt/Swiss-Prot:Q9NZV6

Protein names

SELR, SELX, SepR, SEPX1, HSPC270

Protein function

Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases, methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residue. Acts as a regulator of actin assembly by reducing methionine (R)-sulfoxide mediated by MICALs (MICAL1, MICAL2 or MICAL3) on actin, thereby promoting filament repolymerization. Plays a role in innate immunity by reducing oxidized actin, leading to actin repolymerization in macrophages (By similarity).

Protein sequence and domain

Belongs to the MsrB Met sulfoxide reductase family.; Contains 1 MsrB (methionine-R-sulfoxide reductase) domain.

Protein cellular localization

Cytoplasm . Nucleus . Cytoplasm, cytoskeleton .

Background

This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3′ UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This protein belongs to the methionine sulfoxide reductase (Msr) protein family which includes repair enzymes that reduce oxidized methionine residues in proteins. The protein encoded by this gene is expressed in a variety of adult and fetal tissues and localizes to the cell nucleus and cytosol.

Note

AntibodyPlus can customize MSRB1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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