Rabbit polyclonal MTF2 antibody (A7077)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal MTF2 antibody (A7077)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:100

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

Expand

M96 antibody, PCL2 antibody, TDRD19A antibody, dJ976O13.2 antibody
DJ976O13.2 antibody|hPCl2 antibody|M96 antibody|metal regulatory transcription factor 2 antibody|Metal response element binding transcription factor 2 antibody|metal-response element DNA-binding protein M96 antibody|PCL2 antibody|polycomb-like 2 antibody|polycomb-like protein 2 antibody|Putative DNA binding protein antibody|RP5 976O13.1 antibody|RP5-976O13.1 antibody|TDRD19A antibody|tudor domain containing 19A antibody|Anti-MTF2 antibody (ab42508)

SCBT cat No: sc-165040|

Name

Rabbit polyclonal MTF2 antibody

Catalogue No.

A7077

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human MTF2

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:100

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 67kDa/Observed: Refer to figures

Formulation

MTF2 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

MTF2 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

M96 antibody, PCL2 antibody, TDRD19A antibody, dJ976O13.2 antibody

Database links

Human UniProt/Swiss-Prot:Q9Y483

Protein names

M96, PCL2, TDRD19A, dJ976O13.2

Protein function

Polycomb group (PcG) that specifically binds histone H3 trimethylated at ‘Lys-36’ (H3K36me3) and recruits the PRC2 complex. Acts by binding to H3K36me3, a mark for transcriptional activation, and recruiting the PRC2 complex, leading to enhance PRC2 H3K27me3 methylation activity. Regulates the transcriptional networks during embryonic stem cell self-renewal and differentiation. Promotes recruitment of the PRC2 complex to the inactive X chromosome in differentiating XX ES cells and PRC2 recruitment to target genes in undifferentiated ES cells. Required to repress Hox genes by enhancing H3K27me3 methylation of the PRC2 complex. In some conditions may act as an inhibitor of PRC2 activity: able to activate the CDKN2A gene and promote cellular senescence by suppressing the catalytic activity of the PRC2 complex locally. Binds to the metal-regulating-element (MRE) of MT1A gene promoter (By similarity).

Protein sequence and domain

The Tudor domain recognizes and binds H3K36me3 .Belongs to the Polycomblike family.; Contains 2 PHD-type zinc fingers.; Contains 1 Tudor domain.

Protein cellular localization

Nucleus .

Note

AntibodyPlus can customize MTF2 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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