Rabbit polyclonal MTMR2 antibody (A8993)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal MTMR2 antibody (A8993)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:500 – 1:2000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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CMT4B antibody|OTTHUMP00000204445 antibody|OTTHUMP00000204446 antibody|OTTHUMP00000204447 antibody|OTTHUMP00000204448 antibody|Phosphatidylinositol 3 phosphate phosphatase antibody|Phosphatidylinositol 3,5 bisphosphate 3 phosphatase antibody|Anti-MTMR2 antibody – N-terminal (ab192927)

SCBT cat No: sc-365185|sc-271607|sc-365184|

Name

Rabbit polyclonal MTMR2 antibody

Catalogue No.

A8993

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human MTMR2

Host

Rabbit

Applications

WB

Recommended dilution

WB 1:500 – 1:2000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 73kDa/Observed: Refer to figures

Formulation

MTMR2 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

MTMR2 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Database links

Human UniProt/Swiss-Prot:Q13614

Protein function

Phosphatase that acts on lipids with a phosphoinositol headgroup. Has phosphatase activity towards phosphatidylinositol 3-phosphate and phosphatidylinositol 3,5-bisphosphate.

Protein sequence and domain

The coiled-coil domain mediates interaction with SBF2.Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.; Contains 1 GRAM domain.; Contains 1 myotubularin phosphatase domain.

Protein post-translational modifications

Phosphorylation at Ser-58 decreases MTMR2 localization to endocytic vesicular structures.

Protein cellular localization

Cytoplasm . Early endosome membrane ; Peripheral membrane protein . Note: Partly associated with membranes.

Background

This gene is a member of the myotubularin family of phosphoinositide lipid phosphatases. The encoded protein possesses phosphatase activity towards phosphatidylinositol-3-phosphate and phosphatidylinositol-3,5-bisphosphate. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4B, an autosomal recessive demyelinating neuropathy. Alternatively spliced transcript variants encoding multiple isoforms have been found for this gene. [provided by RefSeq, Aug 2011]

Note

AntibodyPlus can customize MTMR2 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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