Rabbit polyclonal MVP antibody (A1980)


Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

-$50 as credit for submitting review for primary antibody
Shipping notice:
Product will be delivered in 6 to 8 Business Days

Rabbit polyclonal MVP antibody (A1980)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal MVP antibody.

Alternative names:

Check alternative names for the antibody


LRP antibody, VAULT1 antibody
LRP antibody|Major vault protein antibody|Major vault protein, rat, homolog of antibody|MVP antibody|MVP_HUMAN antibody|testicular secretory protein Li 30 antibody|VAULT 1 antibody|VAULT1 antibody|Anti-MVP antibody [EPR13227(B)] (ab175239)

SCBT cat No: sc-23916|sc-23917|sc-135975|sc-390134|sc-390141|sc-18701|sc-366042|sc-18700|


Rabbit polyclonal MVP antibody

Catalogue No.



Human, Mouse, Rat


Recombinant protein of human MVP





Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200







Molecular weight

Predicted: 99kDa/Observed: Refer to Figures


MVP antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.


MVP antibody was purified using affinity purification.


Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

LRP antibody, VAULT1 antibody

Database links

Human UniProt/Swiss-Prot:Q14764

Protein names


Protein function

Required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo-cytoplasmic transport. Down-regulates INFG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases.

Protein tissue specificity

Present in most normal tissues. Higher expression observed in epithelial cells with secretory and excretory functions, as well as in cells chronically exposed to xenobiotics, such as bronchial cells and cells lining the intestine. Overexpressed in many multidrug-resistant cancer cells.

Protein sequence and domain

MVP 3 mediates interaction with PTEN.; MVP 4 mediates interaction with PARP4.Contains 9 MVP (vault) repeats.

Protein post-translational modifications

Phosphorylated on Tyr residues after EGF stimulation.; Dephosphorylated by PTPN11.

Protein cellular localization

Cytoplasm . Nucleus, nuclear pore complex . Cytoplasm, perinuclear region . Note: 5% found in the nuclear pore complex . Translocates from the nucleus to the cytoplasm upon EGF treatment .


This gene encodes the major component of the vault complex. Vaults are multi-subunit ribonucleoprotein structures that may be involved in nucleo-cytoplasmic transport. The encoded protein may play a role in multiple cellular processes by regulating the MAP kinase, JAK/STAT and phosphoinositide 3-kinase/Akt signaling pathways. The encoded protein also plays a role in multidrug resistance, and expression of this gene may be a prognostic marker for several types of cancer. Alternatively spliced transcript variants have been observed for this gene.


AntibodyPlus can customize MVP antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody


ABclonal Inc.


There are no reviews yet.

Only logged in customers who have purchased this product may leave a review

There are no reviews for this product yet.
By submitting a review, get following benefits:

1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!

view database submit reviews

There is no extra validation for this product yet.
Check other extra validated antibodies below:

Welcome to AntibodyPlus!